XYLT1

Gene Symbol	XYLT1
Entrez Gene	64131
Alt Symbol	DBQD2, PXYLT1, XT-I, XT1, XTI, XYLTI
Species	Human
Gene Type	protein-coding
Description	xylosyltransferase I
Other Description	O-xylosyltransferase 1|beta-D-xylosyltransferase 1|peptide O-xylosyltransferase 1|xylT-I|xylosyltransferase 1|xylosyltransferase iota
Swissprots	Q9H1B6 Q86Y38
Accessions	AIZ49756 AJM90214 EAW50949 Q86Y38 AI524006 AJ277441 CAC16787 AJ539163 CAD62248 AK000198 AL050125 BC036692 BC045778 BC156039 AAI56040 BU620961 BX647541 XM_011522574 XP_011520876 NM_022166 NP_071449
Function	Catalyzes the first step in biosynthesis of glycosaminoglycan. Transfers D-xylose from UDP-D-xylose to specific serine residues of the core protein. Initial enzyme in the biosynthesis of chondroitin sulfate and dermatan sulfate proteoglycans in fibroblasts and chondrocytes.
Subcellular Location	Endoplasmic reticulum membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}. Golgi apparatus membrane {ECO:0000269|PubMed:16571645}; Single- pass type II membrane protein {ECO:0000250}. Secreted {ECO:0000305|PubMed:10383739}. Note=Some fraction is also found in the extracellular space together with chondroitin sulfate proteoglycans, suggesting that it can be secreted.
Tissue Specificity	Widely expressed. Expressed at higher level in placenta, kidney and pancreas. Weakly expressed in skeletal muscle. {ECO:0000269|PubMed:11099377}.
Top Pathways	Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate, Glycosaminoglycan biosynthesis - heparan sulfate / heparin

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

XYLT1 / XylT-I Antibody Blocking Peptide - LS-E1933 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

XYLT1 / XylT-I Antibody Blocking Peptide - LS-E17937 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human xylosyltransferase 1 Protein - H00064131-G01-10ug from Novus Biologicals Category Protein Prices $569.00 Sizes 10 µg Species Human

XYLT1-Antibody-N-term-Blocking-peptide - BP12779a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

XYLT1 Blocking Peptide - 33R-7986 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

Recombinant Human Xylosyltransferase 1(XYLT1) ,partial - CSB-YP773057HU CSB-EP773057HU CSB-BP773057HU CSB-MP773057HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

Xylosyltransferase 1(XYLT1) ,partial, Recombinant Protein - MBS1433971 from MyBioSource Category Protein Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

xylosyltransferase 1 Protein - NBP1-90675PEP from Novus Biologicals Category Protein Prices $209.00 Sizes 100 µl Species Human

xylosyltransferase 1 Recombinant Protein Antigen - NBP1-90674PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

XYLT1 Peptide, Human - M34GP17605H from Creative Peptides Category Peptide Source Synthetic. Species Human

Recombinant Xylosyltransferase I (XYLT1) - RPU54714 from Biomatik Category Protein Prices $220.00, $473.00, $722.00, $902.00 Sizes 10 µg, 50 µg, 100 µg, 200 µg Source E.coli Species Human

Recombinant Human XYLT1 protein, His & T7-tagged - XYLT1-1709H from Creative Biomart Category Protein Source E. coli Species Human

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