| Gene Symbol |
DECR1
|
| Entrez Gene |
1666
|
| Alt Symbol |
DECR, NADPH, SDR18C1
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
2,4-dienoyl CoA reductase 1, mitochondrial
|
| Other Description |
2,4-dienoyl-CoA reductase, mitochondrial|4-enoyl-CoA reductase|short chain dehydrogenase/reductase family 18C member 1|short chain dehydrogenase/reductase family 18C, member 1
|
| Swissprots |
Q93085 B7Z6B8 Q2M304 Q16698
|
| Accessions |
AAB88724 AAC14671 AAC62233 EAW91662 EAW91663 EAW91664 Q16698 AK300069 BAH13204 BC105080 AAI05081 BC105082 AAI05083 BC143669 L26050 AAA67551 U49352 AAB09423 XM_005250808 XP_005250865 XM_011516880 XP_011515182 NM_001359 NP_001350
|
| Function |
Auxiliary enzyme of beta-oxidation. It participates in the metabolism of unsaturated fatty enoyl-CoA esters having double bonds in both even- and odd-numbered positions. Catalyzes the NADP-dependent reduction of 2,4-dienoyl-CoA to yield trans-3- enoyl-CoA.
|
| Subcellular Location |
Mitochondrion.
|
| Tissue Specificity |
Heart = liver = pancreas > kidney >> skeletal muscle = lung. {ECO:0000269|PubMed:7818482}.
|
![Western Blot: DECR1 Overexpression Lysate (Adult Normal) [NBL1-09812] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for DECR1.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/4868_DECR1%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-09812-img0002.jpg)