| Gene Symbol | DECR1 |
|---|---|
| Entrez Gene | 1666 |
| Alt Symbol | DECR, NADPH, SDR18C1 |
| Species | Human |
| Gene Type | protein-coding |
| Description | 2,4-dienoyl CoA reductase 1, mitochondrial |
| Other Description | 2,4-dienoyl-CoA reductase, mitochondrial|4-enoyl-CoA reductase|short chain dehydrogenase/reductase family 18C member 1|short chain dehydrogenase/reductase family 18C, member 1 |
| Swissprots | Q93085 B7Z6B8 Q2M304 Q16698 |
| Accessions | AAB88724 AAC14671 AAC62233 EAW91662 EAW91663 EAW91664 Q16698 AK300069 BAH13204 BC105080 AAI05081 BC105082 AAI05083 BC143669 L26050 AAA67551 U49352 AAB09423 XM_005250808 XP_005250865 XM_011516880 XP_011515182 NM_001359 NP_001350 |
| Function | Auxiliary enzyme of beta-oxidation. It participates in the metabolism of unsaturated fatty enoyl-CoA esters having double bonds in both even- and odd-numbered positions. Catalyzes the NADP-dependent reduction of 2,4-dienoyl-CoA to yield trans-3- enoyl-CoA. |
| Subcellular Location | Mitochondrion. |
| Tissue Specificity | Heart = liver = pancreas > kidney >> skeletal muscle = lung. {ECO:0000269|PubMed:7818482}. |