Gene Symbol | DECR1 |
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Entrez Gene | 1666 |
Alt Symbol | DECR, NADPH, SDR18C1 |
Species | Human |
Gene Type | protein-coding |
Description | 2,4-dienoyl CoA reductase 1, mitochondrial |
Other Description | 2,4-dienoyl-CoA reductase, mitochondrial|4-enoyl-CoA reductase|short chain dehydrogenase/reductase family 18C member 1|short chain dehydrogenase/reductase family 18C, member 1 |
Swissprots | Q93085 B7Z6B8 Q2M304 Q16698 |
Accessions | AAB88724 AAC14671 AAC62233 EAW91662 EAW91663 EAW91664 Q16698 AK300069 BAH13204 BC105080 AAI05081 BC105082 AAI05083 BC143669 L26050 AAA67551 U49352 AAB09423 XM_005250808 XP_005250865 XM_011516880 XP_011515182 NM_001359 NP_001350 |
Function | Auxiliary enzyme of beta-oxidation. It participates in the metabolism of unsaturated fatty enoyl-CoA esters having double bonds in both even- and odd-numbered positions. Catalyzes the NADP-dependent reduction of 2,4-dienoyl-CoA to yield trans-3- enoyl-CoA. |
Subcellular Location | Mitochondrion. |
Tissue Specificity | Heart = liver = pancreas > kidney >> skeletal muscle = lung. {ECO:0000269|PubMed:7818482}. |
DECR1 CRISPR/Cas9 KO Plasmid (h) - sc-408513 from Santa Cruz Biotechnology
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DECR1 HDR Plasmid (h) - sc-408513-HDR from Santa Cruz Biotechnology
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DECR1 Double Nickase Plasmid (h) - sc-408513-NIC from Santa Cruz Biotechnology
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DECR1 Double Nickase Plasmid (h2) - sc-408513-NIC-2 from Santa Cruz Biotechnology
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DECR1 CRISPR Activation Plasmid (h) - sc-408513-ACT from Santa Cruz Biotechnology
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DECR1 CRISPR Activation Plasmid (h2) - sc-408513-ACT-2 from Santa Cruz Biotechnology
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DECR1 Lentiviral Activation Particles (h) - sc-408513-LAC from Santa Cruz Biotechnology
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DECR1 Lentiviral Activation Particles (h2) - sc-408513-LAC-2 from Santa Cruz Biotechnology
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DECR1 siRNA (h) - sc-77514 from Santa Cruz Biotechnology
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DECR1 shRNA Plasmid (h) - sc-77514-SH from Santa Cruz Biotechnology
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DECR1 shRNA (h) Lentiviral Particles - sc-77514-V from Santa Cruz Biotechnology
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DECR1 RNAi - H00001666-R01 from Novus Biologicals
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MISSION® esiRNA - EHU011881 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN7077 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND7077 from Sigma-Aldrich
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DECR1 siRNA (Human) - CRH1175 from Cohesion Biosciences
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DECR1 - MBS8205829 from MyBioSource
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shRNA set against Human DECR1 (NM_001359.1) - SHH276261 from Creative biogene
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shRNA set against Human DECR1(NM_001359.1) - SHG227737 from Creative biogene
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Human DECR1 siRNA - orb261677 from Biorbyt
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DECR1 shRNA Plasmid (Human) - CHH1175 from Cohesion Biosciences
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DECR1 miRNA 3'UTR clone - MiUTR1H-02747 from Creative biogene
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