Gene Symbol | BRD3 |
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Entrez Gene | 8019 |
Alt Symbol | ORFX, RING3L |
Species | Human |
Gene Type | protein-coding |
Description | bromodomain containing 3 |
Other Description | RING3-like protein|bromodomain-containing 3|bromodomain-containing protein 3 |
Swissprots | Q5T1R7 Q8N5M3 Q92645 Q15059 B1APD9 Q4G5Y3 |
Accessions | EAW88113 EAW88114 EAW88115 Q15059 AA766480 AF052138 AK026880 AK123322 AK299519 BAG61471 AW409970 AY513270 AAS82952 BC010699 BC030095 BC032124 AAH32124 BI545861 D26362 BAA05393 DW413353 XM_005272214 XP_005272271 XM_006717291 XP_006717354 XM_011519052 XP_011517354 NM_007371 NP_031397 |
Function | Binds hyperacetylated chromatin and plays a role in the regulation of transcription, probably by chromatin remodeling and interaction with transcription factors. Regulates transcription by promoting the binding of the transcription factor GATA1 to its targets (By similarity). Regulates transcription of the CCND1 gene. {ECO:0000250, ECO:0000269|PubMed:18406326}. |
Subcellular Location | Nucleus {ECO:0000305}. Note=Detected on chromatin. {ECO:0000250}. |
Tissue Specificity | Ubiquitous. |
BRD3 (N-14) - sc-46809 from Santa Cruz Biotechnology
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BRD3 (H-40) - sc-99192 from Santa Cruz Biotechnology
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BRD3 (C-12) - sc-46808 from Santa Cruz Biotechnology
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BRD3 (2088C3a) - sc-81202 from Santa Cruz Biotechnology
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Anti-BRD3 antibody - ab71815 from Abcam
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Anti-BRD3 antibody - ab56342 from Abcam
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Anti-BRD3 antibody - ab167642 from Abcam
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Anti-BRD3 antibody - ab66002 from Abcam
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Anti-BRD3 antibody [2088C3a] - ab50818 from Abcam
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Anti-BRD3 Antibody - LS-C77294 from LifeSpan Bioscience
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Anti-BRD3 Antibody (N-Terminus) - LS-C31695 from LifeSpan Bioscience
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Anti-BRD3 Antibody (Phe645) - LS-C191980 from LifeSpan Bioscience
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Anti-BRD3 Antibody (C-Terminus, AP) - LS-C275687 from LifeSpan Bioscience
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Anti-BRD3 Antibody (C-Terminus, APC) - LS-C275690 from LifeSpan Bioscience
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Anti-BRD3 Antibody (aa647-696) - LS-C110336 from LifeSpan Bioscience
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Anti-BRD3 Antibody (aa611-660) - LS-C119051 from LifeSpan Bioscience
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Anti-BRD3 Antibody (C-Terminus, FITC) - LS-C275691 from LifeSpan Bioscience
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Anti-BRD3 Antibody (C-Terminus, Biotin) - LS-C275692 from LifeSpan Bioscience
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Anti-BRD3 Antibody (C-Terminus, Azide-free, HRP) - LS-C275693 from LifeSpan Bioscience
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Anti-BRD3 Antibody (clone 6C10) - LS-C133531 from LifeSpan Bioscience
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Anti-BRD3 Antibody (C-Terminus, PE) - LS-C275694 from LifeSpan Bioscience
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Anti-BRD3 Antibody (aa275-325) - LS-C289118 from LifeSpan Bioscience
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Anti-BRD3 Antibody (aa451-500) - LS-C201275 from LifeSpan Bioscience
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Anti-BRD3 Antibody (clone 7G6) - LS-C133530 from LifeSpan Bioscience
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Anti-BRD3 Antibody (clone 6E7) - LS-C133529 from LifeSpan Bioscience
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