PAOX

Gene Symbol	PAOX
Entrez Gene	196743
Alt Symbol	PAO
Species	Human
Gene Type	protein-coding
Description	polyamine oxidase (exo-N4-amino)
Other Description	peroxisomal N(1)-acetyl-spermine/spermidine oxidase|peroxisomal N1-acetyl-spermine/spermidine oxidase
Swissprots	Q8N555 Q86WP9 Q6QHG3 Q6QHG4 Q5VWY0 Q6QHG1 Q6QHF9 Q6QHG0 Q6QHG6 Q6QHF8 Q8NCX3 D3DXI6 Q6QHF6 Q6QHF5 Q6QHG5 Q6QHG2 Q6QHF7
Accessions	EAW61340 EAW61341 EAW61342 EAW61343 EAW61344 EAW61345 EAW61346 EAW61347 Q6QHF9 AA280165 AF226657 AAN40706 AF312698 AAO63265 AK124186 AK128001 BAG54616 AL834535 CAD39191 AY358418 AAQ88784 AY541513 AAS64373 AY541514 AAS64374 AY541515 AAS64375 AY541516 AAS64376 AY541517 AAS64377 AY541518 AAS64378 AY541519 AAS64379 AY541520 AAS64380 AY541521 AAS64381 AY541522 AAS64382 AY541523 AAS64383 AY541524 AAS64384 BC032778 AAH32778 BE646315 DQ891313 ABM82239 DQ893351 ABM84277 DQ894497 ABM85423 DQ896670 ABM87669 NM_207125 NM_207126 NM_207129 NM_152911 NP_690875 NM_207127 NP_997010 NM_207128 NP_997011 NR_109763 NR_109764 NR_109765 NR_109766
Function	Flavoenzyme which catalyzes the oxidation of N(1)- acetylspermine to spermidine and is thus involved in the polyamine back-conversion. Can also oxidize N(1)-acetylspermidine to putrescine. Substrate specificity: N(1)-acetylspermine = N(1)- acetylspermidine > N(1),N(12)-diacylspermine >> spermine. Does not oxidize spermidine. Plays an important role in the regulation of polyamine intracellular concentration and has the potential to act as a determinant of cellular sensitivity to the antitumor polyamine analogs.
Subcellular Location	Peroxisome {ECO:0000250}. Cytoplasm {ECO:0000250}.
Tissue Specificity	Widely expressed. Not detected in spleen. Expressed at lower level in neoplastic tissues. {ECO:0000269|PubMed:12477380}.
Top Pathways	Peroxisome

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

PAOX / PAO Antibody Blocking Peptide - LS-E19496 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

PAOX / PAO Antibody Blocking Peptide - LS-E19494 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

PAOX / PAO Antibody Blocking Peptide - LS-E19497 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

PAOX / PAO Antibody Blocking Peptide - LS-E19495 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

PAOX / PAO Antibody Blocking Peptide - LS-E19511 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

PAOX / PAO Antibody Blocking Peptide - LS-E8016 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

PAOX-Antibody-Center-Blocking-peptide - BP5864c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

PAOX Blocking Peptide - 33R-4825 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

PAOX Blocking Peptide - 33R-3850 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

PAOX Blocking Peptide - 33R-3297 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

PAOX Blocking Peptide - 33R-7937 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

PAOX Blocking Peptide - abx064081 from Abbexa Category Peptide Species Human

PAOX fusion protein - Ag4305 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

PAOX fusion protein - ag5777 from Proteintech Group Category Protein Source E. coli-derived, PET28a Species Human

Recombinant Human PAOX, GST-tagged - PAOX-1522H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Polyamine Oxidase (PAOX) - RPG817Mu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Mouse

Recombinant Polyamine Oxidase (PAOX) - RPG817Mu02 from Uscn Life Science Inc. Category Protein Source E.coli Species Mouse

PAOX Blocking Peptide - CBP2887 from Cohesion Biosciences Category Peptide Prices $100.00, $300.00 Sizes 1 mg, 5 mg Species Human

Recombinant Human Peroxisomal N(1)-acetyl-spermine/spermidine oxidase(PAOX) - CSB-YP754301HU CSB-EP754301HU CSB-BP754301HU CSB-MP754301HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

PAOX / PAO (transcript variant 4) - TP321583 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

PAOX / PAO (transcript variant 5) - TP324235 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

Peroxisomal N (1)-acetyl-spermine/spermidine oxidase (PAOX), Recombinant Protein - MBS1462750 from MyBioSource Category Protein Prices $1,445.00, $1,445.00, $1,675.00, $1,675.00, $2,460.00, $2,460.00, $2,900.00, $2,900.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

PAOX Protein - NBP2-13727PEP from Novus Biologicals Category Protein Prices $209.00 Sizes 100 µl Species Human

PAOX peptide - orb218750 from Biorbyt Category Peptide Prices $272.00, $510.00 Sizes 1 mg, 5 mg Species Human

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