PAOX

Gene Symbol PAOX
Entrez Gene 196743
Alt Symbol PAO
Species Human
Gene Type protein-coding
Description polyamine oxidase (exo-N4-amino)
Other Description peroxisomal N(1)-acetyl-spermine/spermidine oxidase|peroxisomal N1-acetyl-spermine/spermidine oxidase
Swissprots Q8N555 Q86WP9 Q6QHG3 Q6QHG4 Q5VWY0 Q6QHG1 Q6QHF9 Q6QHG0 Q6QHG6 Q6QHF8 Q8NCX3 D3DXI6 Q6QHF6 Q6QHF5 Q6QHG5 Q6QHG2 Q6QHF7
Accessions EAW61340 EAW61341 EAW61342 EAW61343 EAW61344 EAW61345 EAW61346 EAW61347 Q6QHF9 AA280165 AF226657 AAN40706 AF312698 AAO63265 AK124186 AK128001 BAG54616 AL834535 CAD39191 AY358418 AAQ88784 AY541513 AAS64373 AY541514 AAS64374 AY541515 AAS64375 AY541516 AAS64376 AY541517 AAS64377 AY541518 AAS64378 AY541519 AAS64379 AY541520 AAS64380 AY541521 AAS64381 AY541522 AAS64382 AY541523 AAS64383 AY541524 AAS64384 BC032778 AAH32778 BE646315 DQ891313 ABM82239 DQ893351 ABM84277 DQ894497 ABM85423 DQ896670 ABM87669 NM_207125 NM_207126 NM_207129 NM_152911 NP_690875 NM_207127 NP_997010 NM_207128 NP_997011 NR_109763 NR_109764 NR_109765 NR_109766
Function Flavoenzyme which catalyzes the oxidation of N(1)- acetylspermine to spermidine and is thus involved in the polyamine back-conversion. Can also oxidize N(1)-acetylspermidine to putrescine. Substrate specificity: N(1)-acetylspermine = N(1)- acetylspermidine > N(1),N(12)-diacylspermine >> spermine. Does not oxidize spermidine. Plays an important role in the regulation of polyamine intracellular concentration and has the potential to act as a determinant of cellular sensitivity to the antitumor polyamine analogs.
Subcellular Location Peroxisome {ECO:0000250}. Cytoplasm {ECO:0000250}.
Tissue Specificity Widely expressed. Not detected in spleen. Expressed at lower level in neoplastic tissues. {ECO:0000269|PubMed:12477380}.
Top Pathways Peroxisome

PAOX (A-21) - sc-133881 from Santa Cruz Biotechnology

Prices $279.00
Sizes 50 µg/0.5 ml
Host Rabbit
Clonality Polyclonal
PAOX (A-21): sc-133881. Western blot analysis of PAOX expression in non-transfected: sc-117752 (A) and mouse PAOX transfected: sc-127297 (B) 293T whole cell lysates.

PAOX (P-14) - sc-240767 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-PAOX antibody - ab75199 from Abcam

Prices $370.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-PAOX antibody (ab75199) at 1 µg/ml (in 5% skim milk / PBS buffer) + Human fetal muscle lysate at 10 µgSecondaryHRP conjugated anti-Rabbit IgG at 1/50000 dilution

Anti-PAOX antibody - ab84951 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-PAOX antibody (ab84951) at 1 µg/ml + Human fetal muscle lysate at 10 µgSecondaryHRP conjugated anti-Rabbit IgG at 1/50000 dilution

Anti-PAOX antibody - ab90062 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-PAOX antibody (ab90062) at 1 µg/ml (in 5% skim milk / PBS buffer) + HT1080 cell lysate at 10 µgSecondaryHRP conjugated anti-Rabbit IgG at 1/50000 dilution

Anti-PAOX antibody - ab157580 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-PAOX antibody (ab157580) at 1 µg/ml + rat pancreas lysate at 10 µg

Anti-PAOX / PAO Antibody (aa474-504, AP) - LS-C265527 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PAOX / PAO Antibody (C-Terminus) - LS-C82771 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Fetal muscle lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.

Anti-PAOX / PAO Antibody (aa474-504, APC) - LS-C265528 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PAOX / PAO Antibody (aa539-588) - LS-C82770 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Fetal muscle lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.

Anti-PAOX / PAO Antibody (aa35-84) - LS-C107973 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
PAOX antibody LS-C107973 Western blot of ACHN lysate.

Anti-PAOX / PAO Antibody (aa474-504, FITC) - LS-C265529 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PAOX / PAO Antibody (aa474-504, Biotin) - LS-C265530 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PAOX / PAO Antibody (aa474-504, Azide-free, HRP) - LS-C265531 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PAOX / PAO Antibody (C-Terminus) - LS-C111547 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
PAOX antibody LS-C111547 Western blot of Jurkat lysate.

Anti-PAOX / PAO Antibody (aa474-504, PE) - LS-C265532 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PAOX / PAO Antibody (aa474-504) - LS-C323775 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PAOX / PAO Antibody (aa101-150) - LS-C170230 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Anti-PAOX / PAO Antibody (aa474-504) - LS-C163356 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal
PAOX antibody immunohistochemistry of formalin-fixed and paraffin-embedded human testis tissue followed by peroxidase-conjugated secondary antibody and DAB staining.

PAOX Antibody - NBP1-70669 from Novus Biologicals

Prices $139.00, $329.00
Sizes 20 µl, 100 µl
Host Rabbit
Clonality Polyclonal

PAOX Antibody - NBP1-70668 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

PAOX Antibody - NBP1-70666 from Novus Biologicals

Prices $139.00, $329.00
Sizes 20 µl, 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: PAOX Antibody [NBP1-70666] - Human Muscle lysate, concentration 0.2-1 ug/ml.

PAOX Antibody - NBP2-13727 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: PAOX Antibody [NBP2-13727] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10<br/>Lane 2: Human cell line RT-4<br/>Lane 3: Human cell line U-251MG sp

PAOX Antibody - NBP1-70667 from Novus Biologicals

Prices $139.00, $329.00
Sizes 20 µl, 100 µl
Host Rabbit
Clonality Polyclonal

PAOX Antibody - H00196743-B01P-50ug from Novus Biologicals

Prices $359.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
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