BAX

Gene Symbol BAX
Entrez Gene 581
Alt Symbol BCL2L4
Species Human
Gene Type protein-coding
Description BCL2-associated X protein
Other Description BCL2-associated X protein omega|Baxdelta2G9|Baxdelta2G9omega|Baxdelta2omega|apoptosis regulator BAX|bcl-2-like protein 4|bcl2-L-4
Swissprots Q9NYG7 Q8WZ49 Q07814 P55269 Q9UCZ7 Q07815 Q9UCZ6 Q07812 Q9UQD6 Q9NR76 A8K4W1
Accessions AAD01415 AAD01416 AAL73333 AAO22992 EAW52415 EAW52416 EAW52417 EAW52418 EAW52419 EAW52420 EAW52421 Q07812 AF007826 AAD22706 AF247393 AAF71267 AF250190 AAF82094 AI565203 AJ417988 CAD10744 AJ586909 CAE52909 AJ586910 CAE52910 AK291076 BAF83765 BC014175 AAH14175 BE396495 BM673184 BM706954 CN281003 HQ889830 ADZ05507 JX524562 AFU81108 KF830846 AIO10778 KF830847 AIO10779 KF830848 AIO10780 L22473 AAA03619 L22474 AAA03620 L22475 AAA03621 T29044 U19599 AAC50142 XM_006723314 XP_006723377 XM_011527191 XP_011525493 NM_001291428 NP_001278357 NM_001291429 NP_001278358 NM_001291430 NP_001278359 NM_001291431 NP_001278360 NM_004324 NP_004315 NM_138761 NP_620116 NM_138763 NP_620118 NM_138764 NP_620119 NR_027882 NM_138762
Function Accelerates programmed cell death by binding to, and antagonizing the apoptosis repressor BCL2 or its adenovirus homolog E1B 19k protein. Under stress conditions, undergoes a conformation change that causes translocation to the mitochondrion membrane, leading to the release of cytochrome c that then triggers apoptosis. Promotes activation of CASP3, and thereby apoptosis. {ECO:0000269|PubMed:10772918, ECO:0000269|PubMed:16113678, ECO:0000269|PubMed:18948948, ECO:0000269|PubMed:21199865, ECO:0000269|PubMed:8358790, ECO:0000269|PubMed:8521816}.
Subcellular Location Isoform Gamma: Cytoplasm.
Tissue Specificity Expressed in a wide variety of tissues. Isoform Psi is found in glial tumors. Isoform Alpha is expressed in spleen, breast, ovary, testis, colon and brain, and at low levels in skin and lung. Isoform Sigma is expressed in spleen, breast, ovary, testis, lung, colon, brain and at low levels in skin. Isoform Alpha and isoform Sigma are expressed in pro- myelocytic leukemia, histiocytic lymphoma, Burkitt's lymphoma, T- cell lymphoma, lymphoblastic leukemia, breast adenocarcinoma, ovary adenocarcinoma, prostate carcinoma, prostate adenocarcinoma, lung carcinoma, epidermoid carcinoma, small cell lung carcinoma and colon adenocarcinoma cell lines. {ECO:0000269|PubMed:10772918, ECO:0000269|PubMed:11912183}.
Top Pathways Viral carcinogenesis, Sphingolipid signaling pathway, Non-alcoholic fatty liver disease (NAFLD), Apoptosis, Tuberculosis

Bax ELISA Kit - ab133048 from Abcam

Category ELISA Kit
Prices $625.00
Sizes 1 x 96 tests
Sensitivity = 24.5 pg/ml
Range 62.5 pg/ml - 2000 pg/ml
Representative Standard Curve using ab133048.

Bax Human SimpleStep ELISAâ„¢ Kit - ab199080 from Abcam

Category ELISA Kit
Prices $470.00
Sizes 1 x 96 tests
Sensitivity 0.1 ng/ml
Range 1.6 ng/ml - 100 ng/ml
Background-subtracted data values (mean +/- SD) are graphed.

Human BAX ELISA Kit (Sandwich ELISA) - LS-F4142 from LifeSpan Bioscience

Category ELISA Kit
Prices $690.00
Sizes 1 plate
Sensitivity 0.25 ng/ml
Range 0.781-50 ng/ml

Rat BAX ELISA Kit (Sandwich ELISA) - LS-F5064 from LifeSpan Bioscience

Category ELISA Kit
Prices $740.00
Sizes 1 plate
Sensitivity 12.5 pg/ml
Range 0.781-50 ng/ml

Mouse/Human/Rat BAX ELISA Kit (Cell-Based ELISA) - LS-F1820 from LifeSpan Bioscience

Category ELISA Kit
Prices $450.00
Sizes 1 plate
Range 0.781-50 ng/ml

Mouse BAX ELISA Kit (Sandwich ELISA) - LS-F8604 from LifeSpan Bioscience

Category ELISA Kit
Prices $700.00
Sizes 1 plate
Sensitivity 26.3 pg/ml
Range 0.781-50 ng/ml

Bovine BAX ELISA Kit (Sandwich ELISA) - LS-F8822 from LifeSpan Bioscience

Category ELISA Kit
Prices $820.00
Sizes 1 plate
Sensitivity 0.124 ng/ml
Range 0.781-50 ng/ml

Rat BAX ELISA Kit (Sandwich ELISA) - LS-F10915 from LifeSpan Bioscience

Category ELISA Kit
Prices $600.00
Sizes 1 plate
Sensitivity 0.312
Range 0.781-50 ng/ml

Bovine BAX ELISA Kit (Sandwich ELISA) - LS-F10916 from LifeSpan Bioscience

Category ELISA Kit
Prices $700.00
Sizes 1 plate
Sensitivity 1.56
Range 0.781-50 ng/ml

Human Total Bax-alpha DuoSet IC ELISA - DYC820-2 from R&D Systems

Category ELISA Kit
Prices $329.00, $649.00
Sizes 1 kit (for 2 Plates), 1 kit (for 5 Plates)
Range 312.00 - 20,000 pg/mL

Human Total Bax-alpha DuoSet IC, 5 Plate - DYC820-5 from R&D Systems

Category ELISA Kit

Human Bax ELISA kit - 55R-IB09623 from Fitzgerald

Category ELISA Kit
Prices $795.00
Sizes 96 wells

Human Bax ELISA Kit - abx150790 from Abbexa

Category ELISA Kit
Sensitivity 0.32 ng/ml
Range 0.781 ng/ml - 50 ng/ml

Apoptosis regulator BAX, BAX, Human, ELISA Kit - E1343h from ARP American Research Products

Category ELISA Kit
Prices $576.00
Sizes 96 t
Range 0.312-20 ng/mL

Apoptosis regulator BAX, Human, ELISA Kit - CSB-E09344h from ARP American Research Products

Category ELISA Kit
Prices $450.00, $595.00, $596.00, $599.00
Sizes 48 t, 96 t, 5 x 96t, 10 x 96t
Sensitivity 0.31 ng/ml
Range 1.25 ng/ml-80 ng/ml

Apoptosis regulator BAX, Human, ELISA Kit - E01A1782 from ARP American Research Products

Category ELISA Kit
Prices $535.00, $735.00
Sizes 48 t, 96 t

Bcl-2 Associated X Protein, Bax, Human, ELISA Kit - E-EL-H0562 from ARP American Research Products

Category ELISA Kit
Prices $522.00
Sizes 96 t
Sensitivity 0.469
Range 0.781-50ng/mL

Bax, Human, ELISA - IB09623 from ARP American Research Products

Category ELISA Kit
Prices $773.00
Sizes 96 t

Bcl2 Associated X Protein (Bax), Human, ELISA Kit - SEB343Hu from ARP American Research Products

Category ELISA Kit
Prices $685.00
Sizes 96 t
Sensitivity 0.35ng/mL
Range 0.78 -50ng/mL

Bcl-2 Associated X Protein, Bax, Mouse, ELISA Kit - E-EL-M0178 from ARP American Research Products

Category ELISA Kit
Prices $585.00
Sizes 96 t
Sensitivity 0.094
Range 0.156-10ng/mL

BCL-2 Associated X Protein, BAX, Rat, ELISA Kit - E-EL-R0098 from ARP American Research Products

Category ELISA Kit
Prices $585.00
Sizes 96 t
Sensitivity 0.094
Range 0.156-10ng/mL

Bcl-2 Associated X Protein, Bax, Rabbit, ELISA Kit - E-EL-RB1599 from ARP American Research Products

Category ELISA Kit
Prices $585.00
Sizes 96 t
Sensitivity 46.875
Range 78.125-5000pg/mL

Bcl-2 Associated X Protein, Bax, Chicken, ELISA Kit - E-EL-Ch1023 from ARP American Research Products

Category ELISA Kit
Prices $504.00
Sizes 96 t

Bcl-2 Associated X Protein, Bax, Porcine, ELISA Kit - E-EL-P1049 from ARP American Research Products

Category ELISA Kit
Prices $585.00
Sizes 96 t
Sensitivity 0.375
Range 0.625-40ng/mL

Bcl-2 Associated X Protein, Bax, Guinea Pig, ELISA Kit - E-EL-GP0105 from ARP American Research Products

Category ELISA Kit
Prices $522.00
Sizes 96 t
Sensitivity 0.094
Range 0.156-10ng/mL
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