BSND

Gene Symbol BSND
Entrez Gene 7809
Alt Symbol BART, DFNB73
Species Human
Gene Type protein-coding
Description barttin CLCNK-type chloride channel accessory beta subunit
Other Description Bartter syndrome, infantile, with sensorineural deafness (Barttin)|barttin|deafness, autosomal recessive 73
Swissprots Q8WZ55 Q6NT28
Accessions EAX06661 Q8WZ55 AK129999 AY034632 AAK57750 BC069510 BC103898 AAI03899 BC103899 AAI03900 BC103900 AAI03901 XM_006710883 XP_006710946 NM_057176 NP_476517
Function Functions as a beta-subunit for CLCNKA and CLCNKB chloride channels. In the kidney CLCNK/BSND heteromers mediate chloride reabsorption by facilitating its basolateral efflux. In the stria, CLCNK/BSND channels drive potassium secretion by recycling chloride for the basolateral SLC12A2 cotransporter. {ECO:0000269|PubMed:11734858, ECO:0000269|PubMed:12111250}.
Subcellular Location Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Cytoplasm {ECO:0000250}. Note=A significant amount also observed intracellularly. Staining in membranes of the renal tubule and of potassium-secreting epithelia of the inner ear is basolateral (By similarity). {ECO:0000250}.
Tissue Specificity Expressed primarily in kidney. Expressed in specific nephron segments and in the stria vascularis of the inner ear. {ECO:0000269|PubMed:11687798}.

Barttin (A-1) - sc-271867 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Barttin (A-1): sc-271867. Western blot analysis of Barttin expression in non-transfected: sc-117752 (A) and mouse Barttin transfected: sc-125028 (B) 293T whole cell lysates.

Barttin (S-20) - sc-49611 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Barttin (S-20): sc-49611. Western blot analysis of Barttin expression in rat kidney tissue extract.

Barttin (A-3) - sc-365161 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Barttin (A-3): sc-365161. Western blot analysis of Barttin expression in non-transfected: sc-117752 (A) and mouse Barttin transfected: sc-125028 (B) 293T whole cell lysates.

Barttin (H-208) - sc-367036 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
Barttin (H-208): sc-367036. Western blot analysis of Barttin expression in non-transfected: sc-117752 (A) and mouse Barttin transfected: sc-125028 (B) 293T whole cell lysates.

Barttin (D-20) - sc-49607 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Barttin (G-19) - sc-49609 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-BSND antibody - ab88518 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Anti-BSND antibody (ab88518) at 1 µg/ml + 293 cell lysate at 50 µgSecondaryGoat anti-mouse IgG at 1/5000 dilution

Anti-BSND antibody - ab108150 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-BSND antibody (ab108150) at 1 µg/ml + Human fetal heart lysate at 10 µg

Anti-BSND antibody - ab172136 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-BSND antibody (ab172136) at 1 µg/mlLane 1 : BSND transfected 293T cell line lysateLane 2 : Non-transfected 293T cell line lysateLysates/proteins at 15 µl per lane.SecondaryGoat anti-Rabbit IgG at 1/7500 dilution

Anti-BSND antibody - ab184942 from Abcam

Prices $443.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of Paraffin-embedded Human kidney tissue labeling BSND with ab184942 at 1/1000 dilution.

Anti-BSND antibody [EPR14270] - C-terminal - ab196017 from Abcam

Prices $347.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR14270
Anti-BSND antibody [EPR14270] - C-terminal (ab196017) at 1/1000 dilution + Human fetal kidney lysate at 20 µgSecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/1000 dilution

Anti-BSND / Barttin Antibody (aa292-320, APC) - LS-C212962 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-BSND / Barttin Antibody (aa292-320, AP) - LS-C212959 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-BSND / Barttin Antibody (aa292-320, Biotin) - LS-C212963 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-BSND / Barttin Antibody (aa292-320, FITC) - LS-C212964 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-BSND / Barttin Antibody (aa292-320, Azide-free, HRP) - LS-C212965 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-BSND / Barttin Antibody (aa211-260) - LS-C116885 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
BSND antibody LS-C116885 Western blot of Fetal Heart lysate.

Anti-BSND / Barttin Antibody (aa221-321) - LS-C306580 from LifeSpan Bioscience

Prices $455.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-BSND / Barttin Antibody - LS-C306579 from LifeSpan Bioscience

Prices $455.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

Anti-BSND / Barttin Antibody (aa292-320, PE) - LS-C212966 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-BSND / Barttin Antibody - LS-C309640 from LifeSpan Bioscience

Prices $475.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-BSND / Barttin Antibody - LS-C309639 from LifeSpan Bioscience

Prices $475.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-BSND / Barttin Antibody (aa291-320) - LS-C319892 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-BSND / Barttin Antibody (aa292-320) - LS-C156869 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
BSND Antibody IHC of formalin-fixed and paraffin-embedded mouse kidney tissue followed by peroxidase-conjugated secondary antibody and DAB staining.

BSND Antibody - H00007809-B01P from Novus Biologicals

Prices $359.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Western Blot: BSND Antibody [H00007809-B01P] - Analysis of BSND expression in 293.
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