BSND

Gene Symbol	BSND
Entrez Gene	7809
Alt Symbol	BART, DFNB73
Species	Human
Gene Type	protein-coding
Description	barttin CLCNK-type chloride channel accessory beta subunit
Other Description	Bartter syndrome, infantile, with sensorineural deafness (Barttin)|barttin|deafness, autosomal recessive 73
Swissprots	Q8WZ55 Q6NT28
Accessions	EAX06661 Q8WZ55 AK129999 AY034632 AAK57750 BC069510 BC103898 AAI03899 BC103899 AAI03900 BC103900 AAI03901 XM_006710883 XP_006710946 NM_057176 NP_476517
Function	Functions as a beta-subunit for CLCNKA and CLCNKB chloride channels. In the kidney CLCNK/BSND heteromers mediate chloride reabsorption by facilitating its basolateral efflux. In the stria, CLCNK/BSND channels drive potassium secretion by recycling chloride for the basolateral SLC12A2 cotransporter. {ECO:0000269|PubMed:11734858, ECO:0000269|PubMed:12111250}.
Subcellular Location	Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Cytoplasm {ECO:0000250}. Note=A significant amount also observed intracellularly. Staining in membranes of the renal tubule and of potassium-secreting epithelia of the inner ear is basolateral (By similarity). {ECO:0000250}.
Tissue Specificity	Expressed primarily in kidney. Expressed in specific nephron segments and in the stria vascularis of the inner ear. {ECO:0000269|PubMed:11687798}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human BSND protein fragment - ab167848 from Abcam Category Protein Prices $297.00 Sizes 20 µg Source E. coli Species Human

Human BSND protein fragment - ab159890 from Abcam Category Protein Prices $402.00 Sizes 10 µg Source Wheat germ Species Human

BSND / Barttin Antibody Blocking Peptide - LS-E21800 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

BSND / Barttin Antibody Blocking Peptide - LS-E10357 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human BSND Protein - H00007809-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Recombinant Human BSND Protein - NBP2-22704 from Novus Biologicals Category Protein Prices $269.00 Sizes 20 µg Source E.coli Species Human

BSND-Antibody-C-term-Blocking-Peptide - BP9858b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Human BSND protein - orb191197 from Biorbyt Category Protein Prices $230.00, $442.00, $1,811.00 Sizes 2 μg, 10 μg, 100 μg Source E. coli Species Human

BSND protein (His tag) - 80R-2909 from Fitzgerald Category Protein Prices $275.00 Sizes 20 µg Source E.coli

Barttin (54-320, His-tag) - AR51028PU-N from Acris Antibodies Category Protein Prices $790.00 Sizes 100 µg Source E. coli Species Human

Barttin (54-320, His-tag) - AR51028PU-S from Acris Antibodies Category Protein Prices $340.00 Sizes 20 µg Source E. coli Species Human

Barttin - H00007809-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

Barttin - H00007809-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

BSND, 54-320aa, Human, His tag, E.coli - 01-P2204 from ARP American Research Products Category Protein Prices $139.00, $369.00, $849.00 Sizes 5 µg, 20 µg, 100 µg Species Human

BSND fusion protein - Ag16402 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

BSND fusion protein - ag17220 from Proteintech Group Category Protein Source E. coli-derived, PET28a Species Human

Recombinant Human BSND, GST-tagged - BSND-10305H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Human Bartter syndrome, infantile, with sensorineural deafness (Barttin), His-tagged - BSND-250H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Human Barttin(BSND) - CSB-YP837883HU CSB-EP837883HU CSB-BP837883HU CSB-MP837883HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

BSND, 54-320aa, Human, His tag, E.coli - ATGP2204 from ATGen Category Protein Prices $80.00, $240.00, $720.00 Sizes 4 µg, 20 µg, 100 µg Species Human

BSND Protein - abx163923 from Abbexa Category Protein Species Human

BSND Recombinant Protein Antigen - NBP2-49101PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E. coli Species Human

BSND Peptide, Human - M34GP01554H from Creative Peptides Category Peptide Source Synthetic. Species Human

BSND - PAT-82203-1 from Nordic BioSite Category Protein Species Human

BSND - PAT-82203-2 from Nordic BioSite Category Protein Species Human

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