BSND

Gene Symbol BSND
Entrez Gene 7809
Alt Symbol BART, DFNB73
Species Human
Gene Type protein-coding
Description barttin CLCNK-type chloride channel accessory beta subunit
Other Description Bartter syndrome, infantile, with sensorineural deafness (Barttin)|barttin|deafness, autosomal recessive 73
Swissprots Q8WZ55 Q6NT28
Accessions EAX06661 Q8WZ55 AK129999 AY034632 AAK57750 BC069510 BC103898 AAI03899 BC103899 AAI03900 BC103900 AAI03901 XM_006710883 XP_006710946 NM_057176 NP_476517
Function Functions as a beta-subunit for CLCNKA and CLCNKB chloride channels. In the kidney CLCNK/BSND heteromers mediate chloride reabsorption by facilitating its basolateral efflux. In the stria, CLCNK/BSND channels drive potassium secretion by recycling chloride for the basolateral SLC12A2 cotransporter. {ECO:0000269|PubMed:11734858, ECO:0000269|PubMed:12111250}.
Subcellular Location Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Cytoplasm {ECO:0000250}. Note=A significant amount also observed intracellularly. Staining in membranes of the renal tubule and of potassium-secreting epithelia of the inner ear is basolateral (By similarity). {ECO:0000250}.
Tissue Specificity Expressed primarily in kidney. Expressed in specific nephron segments and in the stria vascularis of the inner ear. {ECO:0000269|PubMed:11687798}.

Barttin CRISPR/Cas9 KO Plasmid (h) - sc-404023 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Barttin HDR Plasmid (h) - sc-404023-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Barttin Double Nickase Plasmid (h) - sc-404023-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Barttin Double Nickase Plasmid (h2) - sc-404023-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Barttin CRISPR Activation Plasmid (h) - sc-404023-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Barttin CRISPR Activation Plasmid (h2) - sc-404023-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Barttin Lentiviral Activation Particles (h) - sc-404023-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Barttin Lentiviral Activation Particles (h2) - sc-404023-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Barttin siRNA (h) - sc-60245 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Barttin shRNA Plasmid (h) - sc-60245-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Barttin shRNA (h) Lentiviral Particles - sc-60245-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU051981 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN4079 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND4079 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR00945 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr00945

BSND siRNA (Human) - CRH5282 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

BSND - MBS8223962 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human BSND (NM_057176.2) - SHH247978 from Creative biogene

Category siRNA
Species Reactivities Human

BSND shRNA Plasmid (Human) - CHH5282 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

BSND miRNA 3'UTR clone - MiUTR1H-00957 from Creative biogene

Species Reactivities Human
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