Gene Symbol | UPK1A |
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Entrez Gene | 11045 |
Alt Symbol | TSPAN21, UP1A, UPIA, UPKA |
Species | Human |
Gene Type | protein-coding |
Description | uroplakin 1A |
Other Description | tetraspanin-21|tspan-21|uroplakin Ia|uroplakin-1a |
Swissprots | Q3KNU5 Q3KNU6 O00322 |
Accessions | AAB57631 AAB62736 O00322 AA548647 AF085807 AAC34887 BC107097 AAI07098 BC107098 AAI07099 HY263470 NM_001281443 NP_001268372 NM_007000 NP_008931 |
Function | Component of the asymmetric unit membrane (AUM); a highly specialized biomembrane elaborated by terminally differentiated urothelial cells. May play an important role in normal bladder epithelial physiology, possibly in regulating membrane permeability of superficial umbrella cells or in stabilizing the apical membrane through AUM/cytoskeletal interactions (By similarity). {ECO:0000250}. |
Subcellular Location | Membrane; Multi-pass membrane protein. |
Tissue Specificity | High expression restricted to ureteric urothelium (most superficial cells); low expression in prostate. Expression in normal urothelial cells is lost in culture. Some expression in tumor cell lines derived from urothelial malignancies. {ECO:0000269|PubMed:15913809, ECO:0000269|PubMed:9846985}. |
UPIa (C-18) - sc-15173 from Santa Cruz Biotechnology
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UPIa (H-127) - sc-366947 from Santa Cruz Biotechnology
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UPIa (N-16) - sc-15170 from Santa Cruz Biotechnology
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Anti-Uroplakin Ia antibody [EPR15498] - ab185970 from Abcam
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Anti-Uroplakin Ia antibody - C-terminal - ab95207 from Abcam
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Anti-UPK1A / Uroplakin 1A Antibody (aa191-217, Biotin) - LS-C273078 from LifeSpan Bioscience
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Anti-UPK1A / Uroplakin 1A Antibody (aa191-217, FITC) - LS-C273079 from LifeSpan Bioscience
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Anti-UPK1A / Uroplakin 1A Antibody (aa191-217, APC) - LS-C273077 from LifeSpan Bioscience
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Anti-UPK1A / Uroplakin 1A Antibody (aa191-217, Azide-free, HRP) - LS-C273080 from LifeSpan Bioscience
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Anti-UPK1A / Uroplakin 1A Antibody (aa191-217, AP) - LS-C273076 from LifeSpan Bioscience
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Anti-UPK1A / Uroplakin 1A Antibody (aa191-217, PE) - LS-C273081 from LifeSpan Bioscience
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Anti-UPK1A / Uroplakin 1A Antibody (aa197-227) - LS-C326205 from LifeSpan Bioscience
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Anti-UPK1A / Uroplakin 1A Antibody (aa191-217) - LS-C160446 from LifeSpan Bioscience
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Uroplakin Ia Antibody - NBP2-14694 from Novus Biologicals
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Rabbit Anti-Uroplakin Ia Polyclonal Antibody - bs-13704R from Bioss
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Rabbit Anti-Uroplakin Ia Polyclonal Antibody, ALEXA FLUOR® 350 Conjugated - bs-13704R-A350 from Bioss
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Rabbit Anti-Uroplakin Ia Polyclonal Antibody, ALEXA FLUOR® 488 Conjugated - bs-13704R-A488 from Bioss
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Rabbit Anti-Uroplakin Ia Polyclonal Antibody, ALEXA FLUOR® 555 Conjugated - bs-13704R-A555 from Bioss
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Rabbit Anti-Uroplakin Ia Polyclonal Antibody, ALEXA FLUOR® 647 Conjugated - bs-13704R-A647 from Bioss
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Rabbit Anti-Uroplakin Ia Polyclonal Antibody, Cy3 Conjugated - bs-13704R-Cy3 from Bioss
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Rabbit Anti-Uroplakin Ia Polyclonal Antibody, Cy5 Conjugated - bs-13704R-Cy5 from Bioss
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Rabbit Anti-Uroplakin Ia Polyclonal Antibody, Cy5.5 Conjugated - bs-13704R-Cy5.5 from Bioss
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Rabbit Anti-Uroplakin Ia Polyclonal Antibody, Cy7 Conjugated - bs-13704R-Cy7 from Bioss
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Rabbit Anti-Uroplakin Ia Polyclonal Antibody, FITC Conjugated - bs-13704R-FITC from Bioss
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Rabbit Anti-Uroplakin Ia Polyclonal Antibody, Biotin Conjugated - bs-13704R-Biotin from Bioss
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