UPK1A

Gene Symbol UPK1A
Entrez Gene 11045
Alt Symbol TSPAN21, UP1A, UPIA, UPKA
Species Human
Gene Type protein-coding
Description uroplakin 1A
Other Description tetraspanin-21|tspan-21|uroplakin Ia|uroplakin-1a
Swissprots Q3KNU5 Q3KNU6 O00322
Accessions AAB57631 AAB62736 O00322 AA548647 AF085807 AAC34887 BC107097 AAI07098 BC107098 AAI07099 HY263470 NM_001281443 NP_001268372 NM_007000 NP_008931
Function Component of the asymmetric unit membrane (AUM); a highly specialized biomembrane elaborated by terminally differentiated urothelial cells. May play an important role in normal bladder epithelial physiology, possibly in regulating membrane permeability of superficial umbrella cells or in stabilizing the apical membrane through AUM/cytoskeletal interactions (By similarity). {ECO:0000250}.
Subcellular Location Membrane; Multi-pass membrane protein.
Tissue Specificity High expression restricted to ureteric urothelium (most superficial cells); low expression in prostate. Expression in normal urothelial cells is lost in culture. Some expression in tumor cell lines derived from urothelial malignancies. {ECO:0000269|PubMed:15913809, ECO:0000269|PubMed:9846985}.

UPIa CRISPR/Cas9 KO Plasmid (h) - sc-402951 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

UPIa HDR Plasmid (h) - sc-402951-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

UPIa Double Nickase Plasmid (h) - sc-402951-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

UPIa Double Nickase Plasmid (h2) - sc-402951-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

UPIa CRISPR Activation Plasmid (h) - sc-402951-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

UPIa CRISPR Activation Plasmid (h2) - sc-402951-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

UPIa Lentiviral Activation Particles (h) - sc-402951-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

UPIa Lentiviral Activation Particles (h2) - sc-402951-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

UPIa siRNA (h) - sc-41090 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

UPIa shRNA Plasmid (h) - sc-41090-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

UPIa shRNA (h) Lentiviral Particles - sc-41090-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU018551 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN22520 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND22520 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

UPK1A siRNA (Human) - CRH7548 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

UPK1A - MBS8201707 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human UPK1A (NM_007000.2) - SHH440777 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human UPK1A(NM_007000.2) - SHL115632 from Creative biogene

Category siRNA
Species Reactivities Human

Human UPK1A siRNA - orb268050 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

UPK1A shRNA Plasmid (Human) - CHH7548 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

UPK1A miRNA 3'UTR clone - MiUTR1H-11026 from Creative biogene

Species Reactivities Human
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