Gene Symbol | HTR7 |
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Entrez Gene | 3363 |
Alt Symbol | 5-HT7 |
Species | Human |
Gene Type | protein-coding |
Description | 5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled |
Other Description | 5-HT-7|5-HT-X|5-hydroxytryptamine (serotonin) receptor 7 (adenylate cyclase-coupled)|5-hydroxytryptamine receptor 7 |
Swissprots | Q5VX02 P78516 P34969 Q5VX01 P78372 B5BUP6 P78336 Q5VX03 |
Accessions | AAB48397 AAF07217 AAF07218 CAA66865 EAW50118 EAW50119 EAW50120 P34969 AB451482 BAG70296 AK292606 BAF85295 AY493988 AAR87480 BC047526 AAH47526 BG108256 L21195 AAC37538 U68487 AAB48393 U68488 AAB48394 NM_000872 NP_000863 NM_019859 NP_062873 NM_019860 NP_062874 |
Function | This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that stimulate adenylate cyclase. |
Subcellular Location | Cell membrane; Multi-pass membrane protein. |
Tissue Specificity | Isoform A is the predominant isoform in spleen, caudate and hippocampus. Isoform B is expressed at lower levels. Isoform D is a minor isoform in term of expression. {ECO:0000269|PubMed:9084407}. |
Top Pathways | Calcium signaling pathway, Neuroactive ligand-receptor interaction |
SR-7 (H-81) - sc-28963 from Santa Cruz Biotechnology
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SR-7 (K-13) - sc-31474 from Santa Cruz Biotechnology
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SR-7 (S-20) - sc-19158 from Santa Cruz Biotechnology
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Anti-5HT7 Receptor antibody - ab61823 from Abcam
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Anti-5HT7 Receptor antibody - ab104860 from Abcam
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Anti-5HT7 Receptor antibody - ab61563 from Abcam
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Anti-5HT7 Receptor antibody - ab129559 from Abcam
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Anti-5HT7 Receptor antibody - ab13898 from Abcam
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Anti-5HT7 Receptor antibody [EPR6271] - ab128892 from Abcam
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Anti-5HT7 Receptor antibody - N-terminal - ab137493 from Abcam
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Anti-HTR7 / 5HT7 Receptor Antibody (N-Terminus) IHC-plus⢠- LS-A658 from LifeSpan Bioscience
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Anti-HTR7 / 5HT7 Receptor Antibody (C-Terminus) IHC-plus⢠- LS-A6675 from LifeSpan Bioscience
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Anti-HTR7 / 5HT7 Receptor Antibody (aa404-433, PE) - LS-C222806 from LifeSpan Bioscience
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Anti-HTR7 / 5HT7 Receptor Antibody (aa404-433) - LS-C329654 from LifeSpan Bioscience
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Anti-HTR7 / 5HT7 Receptor Antibody (aa433-445) - LS-C108099 from LifeSpan Bioscience
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Anti-HTR7 / 5HT7 Receptor Antibody (Extracellular Domain, clone EPR6271) - LS-C152422 from LifeSpan Bioscience
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Anti-HTR7 / 5HT7 Receptor Antibody (C-Terminus) IHC-plus⢠- LS-A6674 from LifeSpan Bioscience
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Anti-HTR7 / 5HT7 Receptor Antibody (aa405-433) - LS-C165087 from LifeSpan Bioscience
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Anti-HTR7 / 5HT7 Receptor Antibody (N-Terminus) IHC-plus⢠- LS-A6673 from LifeSpan Bioscience
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Anti-HTR7 / 5HT7 Receptor Antibody (Cytoplasmic Domain) IHC-plus⢠- LS-A659 from LifeSpan Bioscience
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Anti-HTR7 / 5HT7 Receptor Antibody (C-Terminus) IHC-plus⢠- LS-A7991 from LifeSpan Bioscience
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Anti-HTR7 / 5HT7 Receptor Antibody (C-Terminus) IHC-plus⢠- LS-A663 from LifeSpan Bioscience
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Anti-HTR7 / 5HT7 Receptor Antibody (aa47-96) - LS-C31502 from LifeSpan Bioscience
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Anti-HTR7 / 5HT7 Receptor Antibody (aa47-96) - LS-C30145 from LifeSpan Bioscience
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Anti-HTR7 / 5HT7 Receptor Antibody (aa8-23) - LS-C39057 from LifeSpan Bioscience
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