| Gene Symbol |
HTR7
|
| Entrez Gene |
3363
|
| Alt Symbol |
5-HT7
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled
|
| Other Description |
5-HT-7|5-HT-X|5-hydroxytryptamine (serotonin) receptor 7 (adenylate cyclase-coupled)|5-hydroxytryptamine receptor 7
|
| Swissprots |
Q5VX02 P78516 P34969 Q5VX01 P78372 B5BUP6 P78336 Q5VX03
|
| Accessions |
AAB48397 AAF07217 AAF07218 CAA66865 EAW50118 EAW50119 EAW50120 P34969 AB451482 BAG70296 AK292606 BAF85295 AY493988 AAR87480 BC047526 AAH47526 BG108256 L21195 AAC37538 U68487 AAB48393 U68488 AAB48394 NM_000872 NP_000863 NM_019859 NP_062873 NM_019860 NP_062874
|
| Function |
This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that stimulate adenylate cyclase.
|
| Subcellular Location |
Cell membrane; Multi-pass membrane protein.
|
| Tissue Specificity |
Isoform A is the predominant isoform in spleen, caudate and hippocampus. Isoform B is expressed at lower levels. Isoform D is a minor isoform in term of expression. {ECO:0000269|PubMed:9084407}.
|
| Top Pathways |
Calcium signaling pathway, Neuroactive ligand-receptor interaction
|