NINL

Gene Symbol NINL
Entrez Gene 22981
Alt Symbol NLP, dJ691N24.1
Species Human
Gene Type protein-coding
Description ninein-like
Other Description ninein-like protein
Swissprots Q9NQE3 Q5JYP0 A6NJN0 Q8NE38 B7Z1V8 Q9Y2I6 B3V9H6
Accessions EAX10082 EAX10083 EAX10084 EAX10085 EAX10086 Q9Y2I6 AB023197 BAA76824 AI024623 AK021854 BAB13914 AK093569 AK293991 BAH11644 AK309298 BC036380 AAH36380 EU718622 ACE78295 XM_005260679 XP_005260736 XM_011529186 XP_011527488 XM_011529187 XP_011527489 XM_011529188 XP_011527490 XM_011529189 XP_011527491 XM_011529190 XP_011527492 XM_011529191 XP_011527493 XM_011529192 XP_011527494 XM_011529193 XP_011527495 XM_011529194 XP_011527496 XM_011529195 XP_011527497 XM_011529196 XP_011527498 XM_011529197 XP_011527499 XM_011529198 XP_011527500 NM_025176 NP_079452
Function Involved in the microtubule organization in interphase cells. Overexpression induces the fragmentation of the Golgi, and causes lysosomes to disperse toward the cell periphery; it also interferes with mitotic spindle assembly. May play a role in ovarian carcinogenesis. {ECO:0000269|PubMed:12852856, ECO:0000269|PubMed:16254247, ECO:0000269|PubMed:18538832}.
Subcellular Location Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm. Note=In interphase cells, NINL is transported to the centrosomes by the dynein- dynactin motor complex. During centrosome maturation, PLK1 directly phosphorylates NINL resulting in its release into the cytoplasm.
Tissue Specificity Expressed in KYSE-150 esophageal carcinoma, HeLa cervical carcinoma and U2OS osteosarcoma cells. Expression is regulated in a cell cycle-dependent manner and peaks during G2/M phase (at protein level). Expressed in fetal heart, skeletal muscle, liver, lung and cochlea, and in adult brain, testis, kidney and retina. {ECO:0000269|PubMed:17403670, ECO:0000269|PubMed:18826961}.

NLP (L-20) - sc-85793 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
NLP (L-20): sc-85793. Western blot analysis of NLP expression in TE671 (A) and Jurkat (B) whole cell lysates.

NLP (N-18) - sc-85794 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
NLP (N-18): sc-85794. Western blot analysis of NLP expression in TE671 whole cell lysate.

Anti-NINL antibody - ab121110 from Abcam

Prices $443.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
ab121101 at 1/100 dilution staining NINL in Paraffin-embedded Human Cerebellum tissue by Immunohistochemistry. Note: moderate cytoplasmic positivity in purkinje cells.

Anti-NINL Antibody (aa406-455) - LS-C201509 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot of Human HeLa. NINL antibody dilution 1.0 ug/ml.

NINL Antibody - NBP1-81451 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry: NINL Antibody [NBP1-81451] - Immunohistochemical staining of human cerebellum shows moderate cytoplasmic positivity in purkinje cells.

Anti-NINL antibody produced in rabbit - HPA000686 from Sigma-Aldrich

Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-NLP_HUMAN: <B>Cat. No. HPA000686</B>: Immunoperoxidase staining of formalin-fixed, paraffin-embedded human cerebellum tissue showing cytoplasmic and/or membranous staining of cells in molecular layer as well as Purkinje cells. Note a distinct staining pattern of axons.

NINL Antibody - middle region (ARP46344_P050) - ARP46344_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

NINL Polyclonal Antibody - A7584 from ABclonal

Prices $130.00, $220.00, $380.00
Sizes 50 µl, 100 µl, 200 µl
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts of various cell lines, using NINL antibody.

NINL antibody - orb221740 from Biorbyt

Prices $255.00, $340.00
Sizes 100 μg, 200 μg
Host Rabbit
Clonality Polyclonal

Anti-NINL antibody - STJ29721 from St John's Laboratory Ltd

Host Rabbit
Clonality Polyclonal

Anti-NINL (aa 406-455) polyclonal antibody - DPABH-13127 from Creative Diagnostics

Host Rabbit
Clonality Polyclonal

Anti-NINL (aa 682-787) polyclonal antibody - DPABH-14999 from Creative Diagnostics

Host Rabbit
Clonality Polyclonal

Anti-N. gruberi Nucleolus-Like Particles Monoclonal antibody - DMAB9300 from Creative Diagnostics

Host Mouse
Clonality Monoclonal

Anti-Nucleolus-Like Particles Monoclonal antibody, clone DE6 - DMAB9305 from Creative Diagnostics

Host Mouse
Clonality Monoclonal
Clone DE6

Anti-NINL Antibody - LS-C349314 from LifeSpan Bioscience

Prices $255.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot blot of extracts of various cell lines, using NINL antibody.

NINL - A7584 from NeoScientific

Prices $220.00, $380.00
Sizes 100 µl, 200 µl
Host Rabbit
Clonality Polyclonal

Anti-NINL Antibody (aa406-455) IHC-plus™ - LS-B13145 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Human Adrenal: Formalin-Fixed, Paraffin-Embedded (FFPE)

NINL, Polyclonal Antibody - MBS9128267 from MyBioSource

Prices $230.00, $305.00, $460.00
Sizes 50 µl, 100 µl, 200 µl
Host Rabbit
Clonality Polyclonal

NINL Antibody - abx005880 from Abbexa

Host Rabbit
Clonality Polyclonal

NINL Antibody - CSB-PA896492ESR1HU from Cusabio

Host Rabbit
Clonality Polyclonal

NINL Antibody - CSB-PA896492ESR2HU from Cusabio

Host Rabbit
Clonality Polyclonal

NINL polyclonal antibody - BS70819 from Bioworld Technology

Prices $208.00, $358.00
Sizes 50 µl, 100 µl
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts of various cell lines, using NINL antibody.

NINL Polyclonal Antibody - EAP3452 from Elabscience

Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts of various cell lines, using NINL antibody.

Anti-NINL Antibody A08634 - A08634 from Boster Bio

Prices $299.00
Sizes 1
Host Rabbit
Clonality Polyclonal

Rabbit anti-NINL Antibody - 144-07584-50 from RayBiotech

Prices $200.00, $326.00, $517.00
Sizes 50 µl, 100 µl, 200 µl
Host Rabbit
Western blot analysis of extracts of various cell lines, using NINL antibody.
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