Gene Symbol | RHPN2 |
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Entrez Gene | 85415 |
Alt Symbol | P76RBE, RHOBP |
Species | Human |
Gene Type | protein-coding |
Description | rhophilin, Rho GTPase binding protein 2 |
Other Description | 76 kDa RhoB effector protein|GTP-Rho-binding protein 2|rhophilin 2|rhophilin-2|rhophilin-like Rho-GTPase binding protein |
Swissprots | Q8N9D6 Q8NE33 Q8N3T7 Q96RU1 B3KUY8 Q8IUC4 B4DUS7 B2RCG8 |
Accessions | Q8IUC4 AF268032 AAK58588 AF423421 AAQ04062 AJ347750 CAC87939 AK026894 AK095001 BAC04471 AK098246 BAG53600 AK126506 BAG54339 AK300775 BAG62439 AK315105 BAG37565 AL831950 CAD38597 BC036447 AAH36447 DC348657 DQ892111 ABM83037 DQ895305 ABM86231 NM_033103 NP_149094 |
Function | Binds specifically to GTP-Rho. May function in a Rho pathway to limit stress fiber formation and/or increase the turnover of F-actin structures in the absence of high levels of RhoA activity. {ECO:0000269|PubMed:12221077}. |
Subcellular Location | Cytoplasm, perinuclear region {ECO:0000269|PubMed:12473120}. |
Tissue Specificity | Widely expressed. Highly expressed in prostate, trachea, stomach, colon, thyroid and pancreas. Expressed at lower level in brain, spinal cord, kidney, placenta and liver. {ECO:0000269|PubMed:12221077, ECO:0000269|PubMed:12473120}. |
rhophilin-2 (P-18) - sc-55030 from Santa Cruz Biotechnology
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Anti-RHPN2 Antibody (aa352-380, AP) - LS-C240001 from LifeSpan Bioscience
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Anti-RHPN2 Antibody (aa352-380, Biotin) - LS-C240003 from LifeSpan Bioscience
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Anti-RHPN2 Antibody (aa352-380, APC) - LS-C240004 from LifeSpan Bioscience
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Anti-RHPN2 Antibody (aa352-380, FITC) - LS-C240005 from LifeSpan Bioscience
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Anti-RHPN2 Antibody (aa352-380, PE) - LS-C240009 from LifeSpan Bioscience
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Anti-RHPN2 Antibody (aa352-380, Azide-free, HRP) - LS-C248002 from LifeSpan Bioscience
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Anti-RHPN2 Antibody (aa352-381) - LS-C324676 from LifeSpan Bioscience
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Anti-RHPN2 Antibody (aa352-380) - LS-C158853 from LifeSpan Bioscience
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Anti-RHPN2 Antibody (aa645-655) IHC-plus⢠- LS-B1756 from LifeSpan Bioscience
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Rhophilin 2 Antibody - NB600-792 from Novus Biologicals
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Rhophilin 2 Antibody - NBP2-13231 from Novus Biologicals
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Rhophilin 2 Antibody - H00085415-B01P from Novus Biologicals
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Rhophilin 2 Antibody (1C5) - H00085415-M01 from Novus Biologicals
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Anti-RHPN2 antibody produced in mouse - SAB1409914 from Sigma-Aldrich
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Monoclonal Anti-RHPN2 antibody produced in mouse - SAB1401925 from Sigma-Aldrich
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Anti-RHPN2 antibody produced in goat - SAB2501788 from Sigma-Aldrich
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Anti-RHPN2 (366-380) antibody produced in rabbit - SAB1102696 from Sigma-Aldrich
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Anti-RHPN2 antibody produced in rabbit - HPA051749 from Sigma-Aldrich
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Anti-RHPN2 (641-655) antibody produced in rabbit - SAB1102697 from Sigma-Aldrich
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RHPN2-Antibody-Center - AP19291c from Abgent, a WuXi AppTec company
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Rhophilin-2-Internal-Antibody-internal-region - AF2447a from Abgent, a WuXi AppTec company
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RHPN2 Antibody - middle region (OAAB14867) - OAAB14867 from Aviva Systems Biology
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RHPN2 Antibody (OAEB00429) - OAEB00429 from Aviva Systems Biology
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RHPN2 Antibody (OALA02108) - OALA02108 from Aviva Systems Biology
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