SEH1L

Gene Symbol SEH1L
Entrez Gene 81929
Alt Symbol SEC13L, SEH1A, SEH1B, Seh1
Species Human
Gene Type protein-coding
Description SEH1-like (S. cerevisiae)
Other Description nucleoporin SEH1|nup107-160 subcomplex subunit SEH1|sec13 like protein|sec13-like protein
Swissprots Q96MH3 A8K5B1 Q9C069 Q8NFU6 Q96EE3
Accessions EAX01530 EAX01531 Q96EE3 AF136976 AAG49437 AF255625 AAM21169 AF431970 AAM44214 AF514996 AAM76707 AK056940 BAB71317 AK226075 AK291226 BAF83915 AK314403 BC012430 AAH12430 BX538037 CB990796 HQ447878 ADQ32362 XM_005258152 XP_005258209 XM_011525742 XP_011524044 XM_011525743 XP_011524045 XM_011525744 XP_011524046 XM_011525745 XP_011524047 XM_011525746 XP_011524048 XR_935069 NM_001013437 NP_001013455 NM_031216 NP_112493
Function Component of the Nup107-160 subcomplex of the nuclear pore complex (NPC). The Nup107-160 subcomplex is required for the assembly of a functional NPC. The Nup107-160 subcomplex is also required for normal kinetochore microtubule attachment, mitotic progression and chromosome segregation. This subunit plays a role in recruitment of the Nup107-160 subcomplex to the kinetochore. As a component of the GATOR2 complex, inhibits GATOR1 complex, an inhibitor of the amino acid-sensing branch of the TORC1 pathway. {ECO:0000269|PubMed:15146057, ECO:0000269|PubMed:17363900, ECO:0000269|PubMed:23723238}.
Subcellular Location Chromosome, centromere, kinetochore. Nucleus, nuclear pore complex.
Top Pathways RNA transport

Seh1 CRISPR/Cas9 KO Plasmid (h) - sc-405967 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Seh1 HDR Plasmid (h) - sc-405967-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Seh1 Double Nickase Plasmid (h) - sc-405967-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Seh1 Double Nickase Plasmid (h2) - sc-405967-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Seh1 CRISPR Activation Plasmid (h) - sc-405967-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Seh1 CRISPR Activation Plasmid (h2) - sc-405967-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Seh1 Lentiviral Activation Particles (h) - sc-405967-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Seh1 Lentiviral Activation Particles (h2) - sc-405967-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Seh1 siRNA (h) - sc-76465 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Seh1 shRNA Plasmid (h) - sc-76465-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Seh1 shRNA (h) Lentiviral Particles - sc-76465-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU049161 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN19048 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND19048 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

SEH1L siRNA (Human) - CRJ3085 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

SEH1L - MBS8211374 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human SEH1L (NM_031216.3) - SHH404008 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human SEH1L(NM_031216.3) - SHR212682 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human SEH1L(NM_001013437.1) - SHR212718 from Creative biogene

Category siRNA
Species Reactivities Human

Human SEH1L siRNA - orb273586 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

SEH1L shRNA Plasmid (Human) - CHJ3085 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

SEH1L miRNA 3'UTR clone - MiUTR1H-09238 from Creative biogene

Species Reactivities Human

SEH1L miRNA 3'UTR clone - MiUTR1H-09239 from Creative biogene

Species Reactivities Human
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