SEH1L

Gene Symbol SEH1L
Entrez Gene 81929
Alt Symbol SEC13L, SEH1A, SEH1B, Seh1
Species Human
Gene Type protein-coding
Description SEH1-like (S. cerevisiae)
Other Description nucleoporin SEH1|nup107-160 subcomplex subunit SEH1|sec13 like protein|sec13-like protein
Swissprots Q96MH3 A8K5B1 Q9C069 Q8NFU6 Q96EE3
Accessions EAX01530 EAX01531 Q96EE3 AF136976 AAG49437 AF255625 AAM21169 AF431970 AAM44214 AF514996 AAM76707 AK056940 BAB71317 AK226075 AK291226 BAF83915 AK314403 BC012430 AAH12430 BX538037 CB990796 HQ447878 ADQ32362 XM_005258152 XP_005258209 XM_011525742 XP_011524044 XM_011525743 XP_011524045 XM_011525744 XP_011524046 XM_011525745 XP_011524047 XM_011525746 XP_011524048 XR_935069 NM_001013437 NP_001013455 NM_031216 NP_112493
Function Component of the Nup107-160 subcomplex of the nuclear pore complex (NPC). The Nup107-160 subcomplex is required for the assembly of a functional NPC. The Nup107-160 subcomplex is also required for normal kinetochore microtubule attachment, mitotic progression and chromosome segregation. This subunit plays a role in recruitment of the Nup107-160 subcomplex to the kinetochore. As a component of the GATOR2 complex, inhibits GATOR1 complex, an inhibitor of the amino acid-sensing branch of the TORC1 pathway. {ECO:0000269|PubMed:15146057, ECO:0000269|PubMed:17363900, ECO:0000269|PubMed:23723238}.
Subcellular Location Chromosome, centromere, kinetochore. Nucleus, nuclear pore complex.
Top Pathways RNA transport

Seh1 (N-17) - sc-79054 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Rabbit
Clonality Polyclonal
Seh1 (N-17): sc-79054. Western blot analysis of Seh1 expression in Jurkat (A), A549 (B) and MCF7 (C) whole cell lysates and mouse thymus (D), mouse brain (E) and mouse testis (F) tissue extracts.

Seh1 (Y-19) - sc-79055 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Rabbit
Clonality Polyclonal
Seh1 (Y-19): sc-79055. Western blot analysis of Seh1 expression in mouse thymus tissue extract.

Anti-SEH1L antibody - ab122608 from Abcam

Prices $443.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
ab122608, at 1/50 dilution, staining SEH1L in Paraffin-embedded Human Stomach tissue by Immunohistochemistry.

Anti-SEH1L antibody - N-terminal - ab187307 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-SEH1L antibody - N-terminal (ab187307) at 1/1000 dilution + Mouse thymus total cell extract.

SEH1L Antibody - NBP1-80773 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-SEH1L antibody produced in rabbit - HPA039964 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-SEH1L: <B>Cat. No. HPA039964</B>: Immunohistochemical staining of human stomach, lower shows strong cytoplasmic positivity in glandular cells.

Anti-SEH1L (86-100) antibody produced in rabbit - SAB1102604 from Sigma-Aldrich

Prices $298.50
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Lysates of MDA-MB-231 (lanes 1-2), PC3 (lanes 3-4) and A-549 (lanes 5-6) cells were separated on SDS-PAGE, blotted with Anti-SEH1L (86-100) (<B>Cat. No.SAB1102604</B>) and developed using Goat Anti-Rabbit IgG-Peroxidase (<B>Cat. No. A0545</B>) and a chemiluminescent substrate. <BR/><B>Lanes</B><BR/>1. Antibody dilution 1:250 <BR/>2. Antibody dilution 1:250 + SEH1L immunizing peptide (human, 86-100)<BR/>3. Antibody dilution 1:250 <BR/>4. Antibody dilution 1:250 + SEH1L immunizing peptide (human, 86-100)<BR/>5. Antibody dilution 1:250 <BR/>6. Antibody dilution 1:250 + SEH1L immunizing peptide (human, 86-100)

SEH1 Antibody - N-terminal region (ARP75811_P050) - ARP75811_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-SEH1L (aa 128-199) polyclonal antibody - DPABH-20914 from Creative Diagnostics

Host Rabbit
Clonality Polyclonal

SEH1L antibody - orb186231 from Biorbyt

Prices $255.00, $340.00
Sizes 100 μg, 200 μg
Host Rabbit
Clonality Polyclonal

SEH1 Antibody - N-terminal region : Biotin (ARP75811_P050-Biotin) - ARP75811_P050-Biotin from Aviva Systems Biology

Host Rabbit
Clonality Polyclonal

SEH1 Antibody - N-terminal region : FITC (ARP75811_P050-FITC) - ARP75811_P050-FITC from Aviva Systems Biology

Host Rabbit
Clonality Polyclonal

SEH1 Antibody - N-terminal region : HRP (ARP75811_P050-HRP) - ARP75811_P050-HRP from Aviva Systems Biology

Host Rabbit
Clonality Polyclonal

SEH1L Antibody - middle region (ARP86304_P050) - ARP86304_P050 from Aviva Systems Biology

Host Rabbit
Clonality Polyclonal

SEH1L antibody - orb386930 from Biorbyt

Host Rabbit
Clonality Polyclonal
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