Gene Symbol | Npr1 |
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Entrez Gene | 24603 |
Alt Symbol | Anpra, Gca, NPR-A, Npra |
Species | Rat |
Gene Type | protein-coding |
Description | natriuretic peptide receptor 1 |
Other Description | ANP-A|ANPR-A|GC-A|atrial natriuretic peptide A-type receptor|atrial natriuretic peptide receptor 1|atrial natriuretic peptide receptor A|atrial natriuretic peptide receptor type A|guanylate cyclase A|natriuretic peptide receptor A/guanylate cyclase A (atrionatriuretic peptide receptor A) |
Swissprots | P18910 A1A5N8 |
Accessions | AAA41200 EDM00568 EDM00569 P18910 BC081831 BC128742 AAI28743 M74535 AAA41202 X14773 CAA32881 XM_006232591 XP_006232653 NM_012613 NP_036745 |
Function | Receptor for the atrial natriuretic peptide NPPA/ANP and the brain natriuretic peptide NPPB/BNP which are potent vasoactive hormones playing a key role in cardiovascular homeostasis. Has guanylate cyclase activity upon binding of the ligand (By similarity). {ECO:0000250}. |
Subcellular Location | Membrane; Single-pass type I membrane protein. |
Top Pathways | Vascular smooth muscle contraction, Oxytocin signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Purine metabolism |
Guanylate Cyclase, Soluble - MBS633150 from MyBioSource
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Guanylate Cyclase, Soluble, Monoclonal Antibody - MBS609530 from MyBioSource
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Guanylate Cyclase, Intestinal, Polyclonal Antibody - MBS620102 from MyBioSource
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Guanylate Cyclase, Intestinal, Polyclonal Antibody - MBS619410 from MyBioSource
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Phospho-PGCA - MBS540306 from MyBioSource
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Monoclonal Antibody to Natriuretic Peptide Receptor 1 (NPR1) - MAC665Ra21 from Cloud-clone
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Polyclonal Antibody to Natriuretic Peptide Receptor 1 (NPR1) - PAC665Ra01 from Cloud-clone
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NPRA antibody - orb101546 from Biorbyt
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