Gene Symbol | Npr1 |
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Entrez Gene | 24603 |
Alt Symbol | Anpra, Gca, NPR-A, Npra |
Species | Rat |
Gene Type | protein-coding |
Description | natriuretic peptide receptor 1 |
Other Description | ANP-A|ANPR-A|GC-A|atrial natriuretic peptide A-type receptor|atrial natriuretic peptide receptor 1|atrial natriuretic peptide receptor A|atrial natriuretic peptide receptor type A|guanylate cyclase A|natriuretic peptide receptor A/guanylate cyclase A (atrionatriuretic peptide receptor A) |
Swissprots | P18910 A1A5N8 |
Accessions | AAA41200 EDM00568 EDM00569 P18910 BC081831 BC128742 AAI28743 M74535 AAA41202 X14773 CAA32881 XM_006232591 XP_006232653 NM_012613 NP_036745 |
Function | Receptor for the atrial natriuretic peptide NPPA/ANP and the brain natriuretic peptide NPPB/BNP which are potent vasoactive hormones playing a key role in cardiovascular homeostasis. Has guanylate cyclase activity upon binding of the ligand (By similarity). {ECO:0000250}. |
Subcellular Location | Membrane; Single-pass type I membrane protein. |
Top Pathways | Vascular smooth muscle contraction, Oxytocin signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Purine metabolism |
Recombinant Natriuretic Peptide Receptor 1 (NPR1) - RPC665Ra01 from Cloud-clone
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Recombinant Rat Atrial natriuretic peptide receptor 1(Npr1) - CSB-YP016023RA CSB-EP016023RA CSB-BP016023RA CSB-MP016023RA from Cusabio
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Atrial natriuretic peptide receptor 1(Npr1) , Recombinant Protein - MBS956316 from MyBioSource
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Recombinant Rat NPR1 Protein - NPR1-4049R from Creative Biomart
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