| Gene Symbol | Npr1 |
|---|---|
| Entrez Gene | 24603 |
| Alt Symbol | Anpra, Gca, NPR-A, Npra |
| Species | Rat |
| Gene Type | protein-coding |
| Description | natriuretic peptide receptor 1 |
| Other Description | ANP-A|ANPR-A|GC-A|atrial natriuretic peptide A-type receptor|atrial natriuretic peptide receptor 1|atrial natriuretic peptide receptor A|atrial natriuretic peptide receptor type A|guanylate cyclase A|natriuretic peptide receptor A/guanylate cyclase A (atrionatriuretic peptide receptor A) |
| Swissprots | P18910 A1A5N8 |
| Accessions | AAA41200 EDM00568 EDM00569 P18910 BC081831 BC128742 AAI28743 M74535 AAA41202 X14773 CAA32881 XM_006232591 XP_006232653 NM_012613 NP_036745 |
| Function | Receptor for the atrial natriuretic peptide NPPA/ANP and the brain natriuretic peptide NPPB/BNP which are potent vasoactive hormones playing a key role in cardiovascular homeostasis. Has guanylate cyclase activity upon binding of the ligand (By similarity). {ECO:0000250}. |
| Subcellular Location | Membrane; Single-pass type I membrane protein. |
| Top Pathways | Vascular smooth muscle contraction, Oxytocin signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Purine metabolism |