Gene Symbol | Eid2 |
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Entrez Gene | 386655 |
Alt Symbol | Cri2, EID-2 |
Species | Mouse |
Gene Type | protein-coding |
Description | EP300 interacting inhibitor of differentiation 2 |
Other Description | CREBBP/EP300 inhibitor 2|CREBBP/EP300 inhibitory protein 2|E1A like inhibitor of differentiation 2|EID-1-like inhibitor of differentiation 2|EP300-interacting inhibitor of differentiation 2|eid2 |
Swissprots | Q6X7S9 |
Accessions | Q6X7S9 AY251273 AAP12560 BC094513 AAH94513 NM_198425 NP_940817 |
Function | Interacts with EP300 and acts as a repressor of MYOD- dependent transcription and muscle differentiation. Inhibits EP300 histone acetyltransferase activity. Acts as a repressor of TGFB/SMAD transcriptional responses. May act as a repressor of the TGFB/SMAD3-dependent signaling by selectively blocking formation of TGFB-induced SMAD3-SMAD4 complex (By similarity). {ECO:0000250|UniProtKB:Q8N6I1}. |
Subcellular Location | Nucleus {ECO:0000250|UniProtKB:Q8N6I1}. |
Tissue Specificity | Expressed in heart, brain, kidney and pancreas. Not detected in placenta. {ECO:0000269|PubMed:14585496}. |
Recombinant Mouse EP300-interacting inhibitor of differentiation 2(Eid2) - CSB-YP761545MO CSB-EP761545MO CSB-BP761545MO CSB-MP761545MO from Cusabio
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Recombinant Mouse EID2 Protein - EID2-5067M from Creative Biomart
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EP300-interacting inhibitor of differentiation 2 (Eid2), Recombinant Protein - MBS1414808 from MyBioSource
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