Gene Symbol | Eid2 |
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Entrez Gene | 386655 |
Alt Symbol | Cri2, EID-2 |
Species | Mouse |
Gene Type | protein-coding |
Description | EP300 interacting inhibitor of differentiation 2 |
Other Description | CREBBP/EP300 inhibitor 2|CREBBP/EP300 inhibitory protein 2|E1A like inhibitor of differentiation 2|EID-1-like inhibitor of differentiation 2|EP300-interacting inhibitor of differentiation 2|eid2 |
Swissprots | Q6X7S9 |
Accessions | Q6X7S9 AY251273 AAP12560 BC094513 AAH94513 NM_198425 NP_940817 |
Function | Interacts with EP300 and acts as a repressor of MYOD- dependent transcription and muscle differentiation. Inhibits EP300 histone acetyltransferase activity. Acts as a repressor of TGFB/SMAD transcriptional responses. May act as a repressor of the TGFB/SMAD3-dependent signaling by selectively blocking formation of TGFB-induced SMAD3-SMAD4 complex (By similarity). {ECO:0000250|UniProtKB:Q8N6I1}. |
Subcellular Location | Nucleus {ECO:0000250|UniProtKB:Q8N6I1}. |
Tissue Specificity | Expressed in heart, brain, kidney and pancreas. Not detected in placenta. {ECO:0000269|PubMed:14585496}. |
EID-2 CRISPR/Cas9 KO Plasmid (m) - sc-436455 from Santa Cruz Biotechnology
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EID-2 HDR Plasmid (m) - sc-436455-HDR from Santa Cruz Biotechnology
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EID-2 Double Nickase Plasmid (m) - sc-436455-NIC from Santa Cruz Biotechnology
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EID-2 Double Nickase Plasmid (m2) - sc-436455-NIC-2 from Santa Cruz Biotechnology
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EID-2 CRISPR Activation Plasmid (m) - sc-436455-ACT from Santa Cruz Biotechnology
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EID-2 CRISPR Activation Plasmid (m2) - sc-436455-ACT-2 from Santa Cruz Biotechnology
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EID-2 Lentiviral Activation Particles (m) - sc-436455-LAC from Santa Cruz Biotechnology
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EID-2 Lentiviral Activation Particles (m2) - sc-436455-LAC-2 from Santa Cruz Biotechnology
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EID-2 siRNA (m) - sc-144607 from Santa Cruz Biotechnology
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EID-2 shRNA Plasmid (m) - sc-144607-SH from Santa Cruz Biotechnology
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EID-2 shRNA (m) Lentiviral Particles - sc-144607-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EMU213041 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN30511 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND30511 from Sigma-Aldrich
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EID2 siRNA (Mouse) - CRN4961 from Cohesion Biosciences
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EID2 - MBS829677 from MyBioSource
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shRNA set against Mouse EID2 (NM_198425.2) - SHH284097 from Creative biogene
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shRNA set against Mouse Eid2(NM_198425.2) - SHH028091 from Creative biogene
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Mouse EID2 siRNA - orb294436 from Biorbyt
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EID2 shRNA Plasmid (Mouse) - CHN4961 from Cohesion Biosciences
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EID2 miRNA 3'UTR clone - MiUTR1M-04303 from Creative biogene
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