SDR16C5

Gene Symbol SDR16C5
Entrez Gene 195814
Alt Symbol RDH#2, RDH-E2, RDHE2
Species Human
Gene Type protein-coding
Description short chain dehydrogenase/reductase family 16C, member 5
Other Description EPHD-2|epidermal retinal dehydrogenase 2|epidermal retinol dehydrogenase 2|retSDR2|retinal short chain dehydrogenase reductase|retinal short-chain dehydrogenase reductase 2|short-chain dehydrogenase/reductase family 16C member 5
Swissprots B4DGK2 Q96LX1 Q330K3 Q8N3Y7 Q8TDV9
Accessions EAW86780 EAW86781 EAW86782 Q8N3Y7 AB083038 BAB91014 AK057667 BAB71545 AK095159 BAG52996 AK294634 BAG57813 AY444559 AAS68535 BC037219 AAH37219 BC064525 AAH64525 XM_005251180 XP_005251237 XM_011517478 XP_011515780 XM_011517479 XP_011515781 NM_138969 NP_620419
Function Oxidoreductase with strong preference for NAD. Active in both the oxidative and reductive directions. Oxidizes all-trans- retinol in all-trans-retinaldehyde. No activity was detected with 11-cis-retinol or 11-cis-retinaldehyde as substrates with either NAD(+)/NADH or NADP(+)/NADPH. {ECO:0000269|PubMed:18926804}.
Subcellular Location Endoplasmic reticulum membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Tissue Specificity Detected in adult lung. Detected at low levels in adult brain, heart, testis, placenta, cervix, pancreas, uterus, stomach, rectum, small intestine, colon, esophagus, thymus, skin, and skin keratinocyte. Expression is higher in psoriasis lesions relative to unaffected skin from psoriasis patients. Detected in fetal kidney, skin and lung. {ECO:0000269|PubMed:12372410}.
Top Pathways Retinol metabolism

RDHE2 (A-14) - sc-87388 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
RDHE2 (A-14): sc-87388. Western blot analysis of RDHE2 expression in HeLa (A) and SHP-77 (B) whole cell lysates.

RDHE2 (36-N) - sc-100591 from Santa Cruz Biotechnology

Prices $279.00
Sizes 50 µg/0.5 ml
Host Mouse
Clonality Monoclonal
RDHE2 (36-N): sc-100591. Western blot analysis of RDHE2 expression in non-transfected: sc-117752 (A) and human RDHE2 transfected: sc-116966 (B) 293T whole cell lysates.

Anti-RDHE2 antibody - ab124114 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-RDHE2 antibody (ab124114) at 1/100 dilution + HepG2 cell line lysates at 35 µg

Anti-RDHE2 antibody - ab87071 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-RDHE2 antibody (ab87071) at 1 µg/ml (in 5% skim milk / PBS buffer) + Transfected 293T cell lysate at 10 µgSecondaryHRP conjugated anti-Rabbit IgG at 1/50000 dilution

Anti-RDHE2 / SDR16C5 Antibody (aa123-151, Biotin) - LS-C240497 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-RDHE2 / SDR16C5 Antibody (aa123-151, APC) - LS-C240495 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-RDHE2 / SDR16C5 Antibody (aa123-151, AP) - LS-C240494 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-RDHE2 / SDR16C5 Antibody (aa123-151, FITC) - LS-C240498 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-RDHE2 / SDR16C5 Antibody (aa123-151, PE) - LS-C240499 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-RDHE2 / SDR16C5 Antibody (aa123-151, Azide-free, HRP) - LS-C248100 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-RDHE2 / SDR16C5 Antibody (aa123-151) - LS-C168919 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
SDR16C5 Antibody western blot of HepG2 cell line lysates (35 ug/lane). The SDR16C5 antibody detected the SDR16C5 protein (arrow).

Anti-RDHE2 / SDR16C5 Antibody (aa122-151) - LS-C324966 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-RDHE2 / SDR16C5 Antibody (aa26-310, Azide-free) - LS-C328507 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal

Anti-RDHE2 / SDR16C5 Antibody (aa179-228) - LS-C102446 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
SDR16C5 / RDHE2 antibody LS-C102446 Western blot of Transfected 293T cell lysate.

SDR16C5 Antibody (3G8) - H00195814-M01 from Novus Biologicals

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 3G8
Western Blot: SDR16C5 Antibody (3G8) [H00195814-M01] - RDHE2 monoclonal antibody (M01), clone 3G8. Analysis of RDHE2 expression in NIH/3T3.

SDR16C5 Antibody - NBP1-87150 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: SDR16C5 Antibody [NBP1-87150] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10. Lane 2: Negative control (vector only transfected HEK293T lysate). Lane 3: Over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (3.1 kDa) in mammalian HEK293T cells).

SDR16C5 Antibody - NBP2-20277 from Novus Biologicals

Prices $349.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: SDR16C5 Antibody [NBP2-20277] - Sample (30 ug of whole cell lysate) A: IMR32 10% SDS PAGE gel, diluted at 1:5000.

SDR16C5 Antibody - H00195814-D01P from Novus Biologicals

Prices $399.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western Blot: SDR16C5 Antibody [H00195814-D01P] - Analysis of RDHE2 expression in mouse liver.

SDR16C5 Antibody - NBP1-56947 from Novus Biologicals

Prices $139.00, $329.00
Sizes 20 µl, 100 µl
Host Rabbit
Clonality Polyclonal

SDR16C5 Antibody - H00195814-B01 from Novus Biologicals

Prices $349.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
Western Blot: SDR16C5 Antibody [H00195814-B01] - analysis of RDHE2 expression in transfected 293T cell line by RDHE2 MaxPab polyclonal antibody (B01). Lane 1: RDHE2 transfected lysate (34.10 KDa). Lane 2: Non-transfected lysate.

SDR16C5 Antibody - H00195814-D01 from Novus Biologicals

Prices $399.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

SDR16C5 Antibody - H00195814-A01 from Novus Biologicals

Host Mouse
Clonality Polyclonal

Anti-SDR16C5 antibody produced in rabbit - HPA025224 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-SDR16C5: <B>Cat. No. HPA025224</B>: Immunohistochemical staining of human stomach shows strong cytoplasmic and membranous positivity in glandular cells.

Anti-RDHE2 antibody produced in rabbit - SAB1410323 from Sigma-Aldrich

Prices $347.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-RDHE2: <B>Cat. No. SAB1410323</B>: Antibody concentration: 1-5 μg/mL. Specific band of ~34.2 kDa using mouse liver lysate.

Monoclonal Anti-RDHE2 antibody produced in mouse - WH0195814M1 from Sigma-Aldrich

Prices $347.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 3G8
<B>Immunoblotting</B><BR/>Monoclonal Anti-RDHE2, <B>Cat. No. WH0195814M1</B> used at the antibody concentration: 1 ~ 5 μg/mL. Specific band of ~34 kDa using Hela NE lysate.
Search more