SDR16C5

Gene Symbol SDR16C5
Entrez Gene 195814
Alt Symbol RDH#2, RDH-E2, RDHE2
Species Human
Gene Type protein-coding
Description short chain dehydrogenase/reductase family 16C, member 5
Other Description EPHD-2|epidermal retinal dehydrogenase 2|epidermal retinol dehydrogenase 2|retSDR2|retinal short chain dehydrogenase reductase|retinal short-chain dehydrogenase reductase 2|short-chain dehydrogenase/reductase family 16C member 5
Swissprots B4DGK2 Q96LX1 Q330K3 Q8N3Y7 Q8TDV9
Accessions EAW86780 EAW86781 EAW86782 Q8N3Y7 AB083038 BAB91014 AK057667 BAB71545 AK095159 BAG52996 AK294634 BAG57813 AY444559 AAS68535 BC037219 AAH37219 BC064525 AAH64525 XM_005251180 XP_005251237 XM_011517478 XP_011515780 XM_011517479 XP_011515781 NM_138969 NP_620419
Function Oxidoreductase with strong preference for NAD. Active in both the oxidative and reductive directions. Oxidizes all-trans- retinol in all-trans-retinaldehyde. No activity was detected with 11-cis-retinol or 11-cis-retinaldehyde as substrates with either NAD(+)/NADH or NADP(+)/NADPH. {ECO:0000269|PubMed:18926804}.
Subcellular Location Endoplasmic reticulum membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Tissue Specificity Detected in adult lung. Detected at low levels in adult brain, heart, testis, placenta, cervix, pancreas, uterus, stomach, rectum, small intestine, colon, esophagus, thymus, skin, and skin keratinocyte. Expression is higher in psoriasis lesions relative to unaffected skin from psoriasis patients. Detected in fetal kidney, skin and lung. {ECO:0000269|PubMed:12372410}.
Top Pathways Retinol metabolism

Human RDHE2 protein fragment - ab140552 from Abcam

Category Protein
Source E. coli
Species Human
15% SDS-PAGE analysis of ab140552 (3µg).

RDHE2 / SDR16C5 Antibody Blocking Peptide - LS-E3692 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

RDHE2 / SDR16C5 Antibody Blocking Peptide - LS-E18963 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

SDR16C5 Recombinant Protein - H00195814-P01 from Novus Biologicals

Category Protein
Prices $369.00
Sizes 10 µg
Species Human

Recombinant Human SDR16C5 Protein - NBP2-23469 from Novus Biologicals

Category Protein
Prices $269.00
Sizes 100 µg
Source E.coli
Species Human
SDS-Page: SDR16C5 Protein [NBP2-23469]

SDR16C5-Antibody-Center-Blocking-Peptide - BP14895c from Abgent, a WuXi AppTec company

Category Peptide
Prices $80.00
Sizes 100 µg

Human SDR16C5 protein - orb169266 from Biorbyt

Category Protein
Prices $170.00, $289.00
Sizes 5 μg, 20 μg
Species Human

RDHE2 Blocking Peptide - 33R-1208 from Fitzgerald

Category Peptide
Prices $130.00
Sizes 100 µg

SDR16C5 protein (His tag) - 80R-2697 from Fitzgerald

Category Protein
Prices $270.00
Sizes 100 µg
Source E.coli

RDHE2 / SDR16C5 (32-269, His-tag) - AR50817PU-N from Acris Antibodies

Category Protein
Prices $790.00
Sizes 500 µg
Source E. coli
Species Human
RDHE2 / SDR16C5

RDHE2 / SDR16C5 (32-269, His-tag) - AR50817PU-S from Acris Antibodies

Category Protein
Prices $340.00
Sizes 100 µg
Source E. coli
Species Human
RDHE2 / SDR16C5

RDHE2 / SDR16C5 - H00195814-P01-10 from Acris Antibodies

Category Protein
Prices $380.00
Sizes 10 µg
Source in vitro transl.
Species Human

RDHE2 / SDR16C5 - H00195814-P01-25 from Acris Antibodies

Category Protein
Prices $500.00
Sizes 25 µg
Source in vitro transl.
Species Human

SDR16C5, 32-269aa, Human, His tag, E.coli - 01-P1993 from ARP American Research Products

Category Protein
Prices $179.00, $369.00, $849.00
Sizes 20 µg, 100 µg, 500 µg
Species Human

SDR16C5 fusion protein - ag5261 from Proteintech Group

Category Protein
Source E. coli-derived, PGEX-4T
Species Human

SDR16C5 Human - PRPS-1392 from NeoScientific

Category Protein
Prices $65.00, $169.00, $3,510.00
Sizes 5 µg, 20 µg, 1 mg
Source E.coli.
Species Human

Recombinant Human SDR16C5, His-tagged - SDR16C5-7549H from Creative Biomart

Category Protein
Source E. coli
Species Human

SDR16C5, 32-269aa, Human, His tag, E.coli - ATGP1993 from ATGen

Category Protein
Prices $80.00, $240.00, $720.00
Sizes 20 µg, 100 µg, 500 µg
Species Human
SDSPAGE

RDHE2 / SDR16C5 - TP306759 from Acris Antibodies

Category Protein
Prices $680.00
Sizes 20 µg
Source HEK293 cells
Species Human
RDHE2 / SDR16C5

SDR16C5 Recombinant Protein Antigen - NBP1-87150PEP from Novus Biologicals

Category Protein
Prices $199.00
Sizes 100 µl
Source E.coli
Species Human

SDR16C5 Peptide, Human - M34GP13925H from Creative Peptides

Category Peptide
Source Synthetic.
Species Human

SDR16C5 - PAT-81992-1 from Nordic BioSite

Category Protein
Species Human

SDR16C5 - PAT-81992-2 from Nordic BioSite

Category Protein
Species Human
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