SDR16C5

Gene Symbol SDR16C5
Entrez Gene 195814
Alt Symbol RDH#2, RDH-E2, RDHE2
Species Human
Gene Type protein-coding
Description short chain dehydrogenase/reductase family 16C, member 5
Other Description EPHD-2|epidermal retinal dehydrogenase 2|epidermal retinol dehydrogenase 2|retSDR2|retinal short chain dehydrogenase reductase|retinal short-chain dehydrogenase reductase 2|short-chain dehydrogenase/reductase family 16C member 5
Swissprots B4DGK2 Q96LX1 Q330K3 Q8N3Y7 Q8TDV9
Accessions EAW86780 EAW86781 EAW86782 Q8N3Y7 AB083038 BAB91014 AK057667 BAB71545 AK095159 BAG52996 AK294634 BAG57813 AY444559 AAS68535 BC037219 AAH37219 BC064525 AAH64525 XM_005251180 XP_005251237 XM_011517478 XP_011515780 XM_011517479 XP_011515781 NM_138969 NP_620419
Function Oxidoreductase with strong preference for NAD. Active in both the oxidative and reductive directions. Oxidizes all-trans- retinol in all-trans-retinaldehyde. No activity was detected with 11-cis-retinol or 11-cis-retinaldehyde as substrates with either NAD(+)/NADH or NADP(+)/NADPH. {ECO:0000269|PubMed:18926804}.
Subcellular Location Endoplasmic reticulum membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Tissue Specificity Detected in adult lung. Detected at low levels in adult brain, heart, testis, placenta, cervix, pancreas, uterus, stomach, rectum, small intestine, colon, esophagus, thymus, skin, and skin keratinocyte. Expression is higher in psoriasis lesions relative to unaffected skin from psoriasis patients. Detected in fetal kidney, skin and lung. {ECO:0000269|PubMed:12372410}.
Top Pathways Retinol metabolism

RDHE2 CRISPR/Cas9 KO Plasmid (h) - sc-414950 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

RDHE2 HDR Plasmid (h) - sc-414950-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

RDHE2 Double Nickase Plasmid (h) - sc-414950-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

RDHE2 Double Nickase Plasmid (h2) - sc-414950-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

RDHE2 CRISPR Activation Plasmid (h) - sc-414950-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

RDHE2 CRISPR Activation Plasmid (h2) - sc-414950-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

RDHE2 Lentiviral Activation Particles (h) - sc-414950-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

RDHE2 Lentiviral Activation Particles (h2) - sc-414950-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

RDHE2 siRNA (h) - sc-77583 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

RDHE2 shRNA Plasmid (h) - sc-77583-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

RDHE2 shRNA (h) Lentiviral Particles - sc-77583-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU030981 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN19009 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND19009 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR09472 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr09472

SDR16C5 siRNA (Human) - CRJ6160 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

SDR16C5 RNAi - H00195814-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

SDR16C5 - MBS8227640 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human SDR16C5 (NM_138969.2) - SHH403484 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human RDHE2(NM_138969.2) - SHR174488 from Creative biogene

Category siRNA
Species Reactivities Human

Human SDR16C5 siRNA - orb276661 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

SDR16C5 shRNA Plasmid (Human) - CHJ6160 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

SDR16C5 miRNA 3'UTR clone - MiUTR1H-08721 from Creative biogene

Species Reactivities Human
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