EFEMP1

Gene Symbol EFEMP1
Entrez Gene 2202
Alt Symbol DHRD, DRAD, FBLN3, FBNL, FIBL-3, MLVT, MTLV, S1-5
Species Human
Gene Type protein-coding
Description EGF containing fibulin-like extracellular matrix protein 1
Other Description EGF-containing fibulin-like extracellular matrix protein 1|extracellular protein S1-5|fibulin-3
Swissprots D6W5D2 B4DW75 A8K3I4 Q12805 Q541U7
Accessions AAK11491 AAX81993 AAY14669 CAJ30876 EAX00080 EAX00081 EAX00082 Q12805 AA704122 AB209212 BAD92449 AI472137 AK092854 BAG52615 AK290599 BAF83288 AK293058 BAF85747 AK301402 BAG62937 AK301531 BAG63032 AK312639 BAG35523 AL703474 BC014410 AAH14410 BC098561 AAH98561 BU542044 BU683304 BX475672 DA264704 DQ892514 ABM83440 DQ895728 ABM86654 U03877 AAA65590 XM_005264205 XP_005264262 NM_001039348 NP_001034437 NM_001039349 NP_001034438 NM_004105
Function Binds EGFR, the EGF receptor, inducing EGFR autophosphorylation and the activation of downstream signaling pathways. May play a role in cell adhesion and migration. May function as a negative regulator of chondrocyte differentiation. In the olfactory epithelium, it may regulate glial cell migration, differentiation and the ability of glial cells to support neuronal neurite outgrowth. {ECO:0000269|PubMed:19804359, ECO:0000269|PubMed:19887559, ECO:0000269|PubMed:20005202}.
Subcellular Location Secreted, extracellular space {ECO:0000250}. Secreted, extracellular space, extracellular matrix {ECO:0000250}. Note=Localizes to the lamina propria underneath the olfactory epithelium. {ECO:0000250}.
Tissue Specificity In the eye, associated with photoreceptor outer and inner segment regions, the nerve fiber layer, outer nuclear layer and inner and outer plexiform layers of the retina. {ECO:0000269|PubMed:12242346, ECO:0000269|PubMed:20005202}.

Fibulin-3 (C-3) - sc-365224 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Fibulin-3 (C-3): sc-365224. Western blot analysis of Fibulin-3 expression in Y79 whole cell lysate.

Fibulin-3 (H-149) - sc-99177 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
Fibulin-3 (H-149): sc-99177. Western blot analysis of Fibulin-3 expression in HUVEC-C whole cell lysate.

Fibulin-3 (mab3-5) - sc-33722 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Fibulin-3 (mab3-5): sc-33722. Western blot analysis of Fibulin-3 expression in ARPE-19 conditioned media.

Fibulin-3 (N-16) - sc-46100 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-EFEMP1 antibody - ab106429 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Lane 1 : Anti-EFEMP1 antibody (ab106429) at 0.5 µg/mlLane 2 : Anti-EFEMP1 antibody (ab106429) at 1 µg/mlLane 1 : HeLa cell lysateLane 2 : HeLa cell lysateLysates/proteins at 15 µg per lane.

Anti-EFEMP1 antibody - ab14926 from Abcam

Prices $370.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Anti-EFEMP1 antibody - ab151976 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-EFEMP1 antibody (ab151976) at 1/1000 dilutionLane 1 : 293T whole cell lysateLane 2 : A431 whole cell lysateLane 3 : H1299 whole cell lysateLysates/proteins at 30 µg per lane.

Anti-EFEMP1 antibody - ab92725 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-EFEMP1 antibody (ab92725) at 1/500 dilutionLane 1 : extracts from Rat lung cellsLane 2 : extracts from Rat lung cells with immunizing peptide at 5 µgLysates/proteins at 10 µg per lane.

Anti-EFEMP1 antibody [1D9] - ab119318 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 1D9
All lanes : Anti-EFEMP1 antibody [1D9] (ab119318) at 1/500 dilutionLane 1 : HEK293T cell lysate transfected with pCMV6-ENTRY controlLane 2 : HEK293T cell lysate transfected with pCMV6-ENTRY EFEMP1 cDNALysates/proteins at 5 µg per lane.

Anti-EFEMP1 antibody - C-terminal - ab200450 from Abcam

Host Rabbit
Clonality Polyclonal
All lanes : Anti-EFEMP1 antibody - C-terminal (ab200450) at 1/1000 dilutionLane 1 : HeLa total cell extractLane 2 : Jurkat total cell extract

Anti-Fibulin-3 / EFEMP1 Antibody (C-Terminus) - LS-C65200 from LifeSpan Bioscience

Prices $650.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-Fibulin-3 / EFEMP1 Antibody (aa119-148, AP) - LS-C222341 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-Fibulin-3 / EFEMP1 Antibody (aa119-148, Biotin) - LS-C222343 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-Fibulin-3 / EFEMP1 Antibody (aa111-160) - LS-C119946 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of extracts from rat lung, using EFEMP1 Antibody. The lane on the right is treated with the synthesized peptide.

Anti-Fibulin-3 / EFEMP1 Antibody (aa119-148, APC) - LS-C222342 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-Fibulin-3 / EFEMP1 Antibody (aa119-148, FITC) - LS-C222344 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-Fibulin-3 / EFEMP1 Antibody (C-Terminus) - LS-C110638 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
EFEMP1 antibody LS-C110638 Western blot of Placenta lysate.

Anti-Fibulin-3 / EFEMP1 Antibody (aa119-148, PE) - LS-C226744 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-Fibulin-3 / EFEMP1 Antibody (Pro150) - LS-C177833 from LifeSpan Bioscience

Prices $345.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of Fibulin-3 (P150) pAb in extracts from rat lung cells.

Anti-Fibulin-3 / EFEMP1 Antibody (aa119-148, Azide-free, HRP) - LS-C222345 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-Fibulin-3 / EFEMP1 Antibody (aa258-493, FITC) - LS-C301833 from LifeSpan Bioscience

Prices $455.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-Fibulin-3 / EFEMP1 Antibody (aa166-445, Biotin) - LS-C301279 from LifeSpan Bioscience

Prices $455.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-Fibulin-3 / EFEMP1 Antibody (aa166-445, FITC) - LS-C304613 from LifeSpan Bioscience

Prices $475.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-Fibulin-3 / EFEMP1 Antibody - LS-C307908 from LifeSpan Bioscience

Prices $455.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

Anti-Fibulin-3 / EFEMP1 Antibody (aa126-156) - LS-C321029 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
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