EFEMP1

Gene Symbol EFEMP1
Entrez Gene 2202
Alt Symbol DHRD, DRAD, FBLN3, FBNL, FIBL-3, MLVT, MTLV, S1-5
Species Human
Gene Type protein-coding
Description EGF containing fibulin-like extracellular matrix protein 1
Other Description EGF-containing fibulin-like extracellular matrix protein 1|extracellular protein S1-5|fibulin-3
Swissprots D6W5D2 B4DW75 A8K3I4 Q12805 Q541U7
Accessions AAK11491 AAX81993 AAY14669 CAJ30876 EAX00080 EAX00081 EAX00082 Q12805 AA704122 AB209212 BAD92449 AI472137 AK092854 BAG52615 AK290599 BAF83288 AK293058 BAF85747 AK301402 BAG62937 AK301531 BAG63032 AK312639 BAG35523 AL703474 BC014410 AAH14410 BC098561 AAH98561 BU542044 BU683304 BX475672 DA264704 DQ892514 ABM83440 DQ895728 ABM86654 U03877 AAA65590 XM_005264205 XP_005264262 NM_001039348 NP_001034437 NM_001039349 NP_001034438 NM_004105
Function Binds EGFR, the EGF receptor, inducing EGFR autophosphorylation and the activation of downstream signaling pathways. May play a role in cell adhesion and migration. May function as a negative regulator of chondrocyte differentiation. In the olfactory epithelium, it may regulate glial cell migration, differentiation and the ability of glial cells to support neuronal neurite outgrowth. {ECO:0000269|PubMed:19804359, ECO:0000269|PubMed:19887559, ECO:0000269|PubMed:20005202}.
Subcellular Location Secreted, extracellular space {ECO:0000250}. Secreted, extracellular space, extracellular matrix {ECO:0000250}. Note=Localizes to the lamina propria underneath the olfactory epithelium. {ECO:0000250}.
Tissue Specificity In the eye, associated with photoreceptor outer and inner segment regions, the nerve fiber layer, outer nuclear layer and inner and outer plexiform layers of the retina. {ECO:0000269|PubMed:12242346, ECO:0000269|PubMed:20005202}.

Human EFEMP1 full length protein - ab114651 from Abcam

Category Protein
Source Wheat germ
Species Human
12.5% SDS-PAGE showing ab114651 at approximately 79.97kDa stained with Coomassie Blue.

Fibulin-3 / EFEMP1 Antibody Blocking Peptide - LS-E30717 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 50 µg

Fibulin-3 / EFEMP1 Antibody Blocking Peptide - LS-E9937 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

Fibulin-3 / EFEMP1 Antibody Blocking Peptide - LS-E15208 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

Fibulin-3 / EFEMP1 Antibody Blocking Peptide - LS-E15209 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

Fibulin-3 / EFEMP1 Antibody Blocking Peptide - LS-E15255 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

Recombinant Human Fibulin-3/EFEMP1 Protein - H00002202-P01 from Novus Biologicals

Category Protein
Prices $319.00
Sizes 2 µg
Source Wheat Germ
Species Human
SDS-Page: Fibulin-3/EFEMP1 Recombinant Protein [H00002202-P01]

Fibulin-3/EFEMP1 Blocking Peptide - NBP1-77040PEP from Novus Biologicals

Category Peptide
Prices $129.00
Sizes 50 µg
Species Human

EFEMP1-Antibody-N-term-Blocking-Peptide - BP9095a from Abgent, a WuXi AppTec company

Category Peptide
Prices $80.00
Sizes 100 µg

Recombinant Human Fibulin 3 (HA Tag), CF - 8416-FB-050 from R&D Systems

Category Protein
Source Chinese Hamster Ovary cell line, CHO-derived, Gln18-Phe493 with N-terminal HA tag

Fibulin-3 peptide - orb108474 from Biorbyt

Category Peptide
Prices $374.00
Sizes 50 μg

EFEMP1 Blocking Peptide - 33R-6674 from Fitzgerald

Category Peptide
Prices $130.00
Sizes 100 µg

EFEMP1 Blocking Peptide - 33R-3444 from Fitzgerald

Category Peptide
Prices $130.00
Sizes 100 µg

EFEMP1 Blocking Peptide - 33R-4746 from Fitzgerald

Category Peptide
Prices $130.00
Sizes 100 µg

Human Fibulin 3 Protein - abx066640 from Abbexa

Category Protein
Source E.coli
Species Human

Fibulin-3 - H00002202-P01-10 from Acris Antibodies

Category Protein
Prices $340.00
Sizes 10 µg
Source in vitro transl.
Species Human

Fibulin-3 - H00002202-P01-25 from Acris Antibodies

Category Protein
Prices $460.00
Sizes 25 µg
Source in vitro transl.
Species Human

Fibulin-3 Control Peptide - AP09988CP-N from Acris Antibodies

Category Peptide
Prices $235.00
Sizes 250 µg

Fibulin-3 Control Peptide - AP30337CP-N from Acris Antibodies

Category Peptide
Prices $135.00
Sizes 50 µg

Fibulin 3 (FBLN3), Human - 20-9072 from ARP American Research Products

Category Protein
Prices $509.00
Sizes 50 µg
Source E.coli
Species Human

EFEMP1 fusion protein - ag1594 from Proteintech Group

Category Protein
Source E. coli-derived, PGEX-4T
Species Human

Recombinant Human EFEMP1 - EFEMP1-27780TH from Creative Biomart

Category Protein
Source Wheat germ
Species Human

Recombinant Human EFEMP1, MYC/DDK-tagged - EFEMP1-501H from Creative Biomart

Category Protein
Source Human 293HEK cells

Recombinant Fibulin 3 (FBLN3) - RPF422Hu01 from Uscn Life Science Inc.

Category Protein
Source E.coli
Species Human

Recombinant Fibulin 3 (FBLN3) - RPF422Mu01 from Uscn Life Science Inc.

Category Protein
Source E.coli
Species Mouse
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