Gene Symbol | AGXT2 |
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Entrez Gene | 64902 |
Alt Symbol | AGT2, DAIBAT |
Species | Human |
Gene Type | protein-coding |
Description | alanine--glyoxylate aminotransferase 2 |
Other Description | (R)-3-amino-2-methylpropionate--pyruvate transaminase|alanine--glyoxylate aminotransferase 2, mitochondrial|beta-ALAAT II|beta-alanine-pyruvate aminotransferase |
Swissprots | Q5W7Q1 Q53G03 B7ZM47 Q9BYV1 Q53FB4 Q53FY7 E9PDL7 |
Accessions | EAW55912 Q9BYV1 AB193309 BAD66662 AJ292204 CAC24841 AK055732 BAG51563 AK055757 BAG51568 AK223128 BAD96848 AK223144 AK223375 BAD97095 AK296109 BAH12259 AK314691 BAG37242 BC144268 AAI44269 BC150603 AAI50604 BC156124 AAI56125 BC156919 AAI56920 BP277413 DA633665 XM_005248337 XP_005248394 XM_005248338 XP_005248395 XM_011514077 XP_011512379 XM_011514078 XP_011512380 NM_001306173 NP_001293102 NM_031900 NP_114106 |
Function | Can metabolize asymmetric dimethylarginine (ADMA) via transamination to alpha-keto-delta-(NN-dimethylguanidino) valeric acid (DMGV). ADMA is a potent inhibitor of nitric-oxide (NO) synthase, and this activity provides mechanism through which the kidney regulates blood pressure. {ECO:0000269|PubMed:20018850, ECO:0000269|PubMed:23023372}. |
Subcellular Location | Mitochondrion {ECO:0000269|PubMed:20018850}. |
Top Pathways | Glycine, serine and threonine metabolism, Alanine, aspartate and glutamate metabolism |
Human AGXT2 protein fragment - ab163900 from Abcam
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AGXT2 Antibody Blocking Peptide - LS-E17709 from LifeSpan Bioscience
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AGXT2 Antibody Blocking Peptide - LS-E10344 from LifeSpan Bioscience
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Recombinant Human AGXT2 Protein - H00064902-Q01 from Novus Biologicals
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AGXT2-Antibody-C-term-Blocking-Peptide - BP9834b from Abgent, a WuXi AppTec company
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AGXT2 Blocking Peptide - 33R-9305 from Fitzgerald
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AGXT2 / AGT2 - H00064902-Q01-10 from Acris Antibodies
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AGXT2 / AGT2 - H00064902-Q01-25 from Acris Antibodies
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Recombinant Human Alanine--glyoxylate aminotransferase 2, mitochondrial(AGXT2) - CSB-YP866322HU CSB-EP866322HU CSB-BP866322HU CSB-MP866322HU from Cusabio
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Alanine--glyoxylate aminotransferase 2, mitochondrial (AGXT2) - MBS1478453 from MyBioSource
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Alanine--glyoxylate aminotransferase 2, mitochondrial (AGXT2) - MBS1412487 from MyBioSource
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AGXT2 / AGT2 - TP319357 from Acris Antibodies
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Recombinant Alanine Glyoxylate Aminotransferase 2 (AGXT2) - RPD855Hu01 from Uscn Life Science Inc.
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Recombinant Alanine Glyoxylate Aminotransferase 2 (AGXT2) - RPD855Mu01 from Uscn Life Science Inc.
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Recombinant Alanine Glyoxylate Aminotransferase 2 (AGXT2) - RPD855Ra01 from Uscn Life Science Inc.
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AGXT2 Recombinant Protein Antigen - NBP1-89199PEP from Novus Biologicals
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AGXT2 Peptide, Human - M34GP00394H from Creative Peptides
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AGXT2 Recombinant Protein (OPCD00477) - OPCD00477 from Aviva Systems Biology
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