Gene Symbol | AGO4 |
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Entrez Gene | 192670 |
Alt Symbol | EIF2C4 |
Species | Human |
Gene Type | protein-coding |
Description | argonaute RISC catalytic component 4 |
Other Description | argonaute 4|argonaute4|eIF-2C 4|eIF2C 4|eukaryotic translation initiation factor 2C, 4|hAgo4|protein argonaute-4 |
Swissprots | A7MD27 Q9HCK5 |
Accessions | EAX07398 EAX07399 EAX07400 Q9HCK5 AB046787 BAB13393 AK000040 BAA90899 AL831908 BC152450 AAI52451 BC160021 AAI60021 BG186585 CA419947 XM_005270578 XP_005270635 XM_005270579 XP_005270636 XM_011540883 XP_011539185 XM_011540884 XP_011539186 XR_246243 XR_246244 XR_946567 NM_017629 NP_060099 |
Function | Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs. Also required for RNA-directed transcription and replication of the human hapatitis delta virus (HDV). {ECO:0000255|HAMAP- Rule:MF_03033, ECO:0000269|PubMed:15337849, ECO:0000269|PubMed:18552826, ECO:0000269|PubMed:18771919}. |
Subcellular Location | Cytoplasm, P-body {ECO:0000255|HAMAP- Rule:MF_03033, ECO:0000269|PubMed:16081698, ECO:0000269|PubMed:19167051}. |
Human Argonaute 4 full length protein - ab131948 from Abcam
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Human Argonaute 4 protein fragment - ab165830 from Abcam
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Recombinant Human Argonaute 4 Protein - H00192670-Q01 from Novus Biologicals
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Recombinant Human Argonaute 4 Protein - H00192670-P01 from Novus Biologicals
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EIF2C4 Blocking Peptide - 33R-1952 from Fitzgerald
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EIF2C4 / AGO4 - H00192670-P01-10 from Acris Antibodies
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EIF2C4 / AGO4 - H00192670-P01-25 from Acris Antibodies
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EIF2C4 / AGO4 - H00192670-Q01-10 from Acris Antibodies
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EIF2C4 / AGO4 - H00192670-Q01-25 from Acris Antibodies
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EIF2C4 fusion protein - ag19257 from Proteintech Group
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EIF2C4 fusion protein - ag19211 from Proteintech Group
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Recombinant Human Protein argonaute-4(EIF2C4) ,partial - CSB-YP864031HU CSB-EP864031HU CSB-BP864031HU CSB-MP864031HU from Cusabio
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Protein argonaute-4 (EIF2C4), partial, Recombinant Protein - MBS1304573 from MyBioSource
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EIF2C4 Peptide, Human - M34GP04807H from Creative Peptides
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Argonaute 4 Recombinant Protein Antigen - NBP2-57022PEP from Novus Biologicals
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