Gene Symbol | AGO4 |
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Entrez Gene | 192670 |
Alt Symbol | EIF2C4 |
Species | Human |
Gene Type | protein-coding |
Description | argonaute RISC catalytic component 4 |
Other Description | argonaute 4|argonaute4|eIF-2C 4|eIF2C 4|eukaryotic translation initiation factor 2C, 4|hAgo4|protein argonaute-4 |
Swissprots | A7MD27 Q9HCK5 |
Accessions | EAX07398 EAX07399 EAX07400 Q9HCK5 AB046787 BAB13393 AK000040 BAA90899 AL831908 BC152450 AAI52451 BC160021 AAI60021 BG186585 CA419947 XM_005270578 XP_005270635 XM_005270579 XP_005270636 XM_011540883 XP_011539185 XM_011540884 XP_011539186 XR_246243 XR_246244 XR_946567 NM_017629 NP_060099 |
Function | Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs. Also required for RNA-directed transcription and replication of the human hapatitis delta virus (HDV). {ECO:0000255|HAMAP- Rule:MF_03033, ECO:0000269|PubMed:15337849, ECO:0000269|PubMed:18552826, ECO:0000269|PubMed:18771919}. |
Subcellular Location | Cytoplasm, P-body {ECO:0000255|HAMAP- Rule:MF_03033, ECO:0000269|PubMed:16081698, ECO:0000269|PubMed:19167051}. |
Argonaute 4 (D10F10) Rabbit mAb - 6913 from Cell Signaling Technology
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eIF2C4 (E-7) - sc-374220 from Santa Cruz Biotechnology
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eIF2C4 (H-241) - sc-366128 from Santa Cruz Biotechnology
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eIF2C4 (C-12) - sc-32665 from Santa Cruz Biotechnology
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eIF2C4 (K-15) - sc-32664 from Santa Cruz Biotechnology
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Anti-Argonaute 4 antibody - ab85077 from Abcam
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Anti-Argonaute 4 with anti-GAPDH internal loading control antibody - ab94772 from Abcam
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Anti-AGO4 / EIF2C4 Antibody (aa627-640) - LS-C47413 from LifeSpan Bioscience
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Anti-AGO4 / EIF2C4 Antibody (aa1-101) - LS-C306131 from LifeSpan Bioscience
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Anti-AGO4 / EIF2C4 Antibody (clone 13A154) - LS-C183369 from LifeSpan Bioscience
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Anti-AGO4 / EIF2C4 Antibody (aa611-660) - LS-C110921 from LifeSpan Bioscience
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Anti-AGO4 / EIF2C4 Antibody - LS-C136889 from LifeSpan Bioscience
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Argonaute 4 Antibody - NBP1-55239 from Novus Biologicals
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Argonaute 4 Antibody (4G3) - H00192670-M08 from Novus Biologicals
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Argonaute 4/eIF2C4 Polyclonal Antibody - bs-12518R from Bioss
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Argonaute 4/eIF2C4 Polyclonal Antibody, ALEXA FLUOR® 350 Conjugated - bs-12518R-A350 from Bioss
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Argonaute 4/eIF2C4 Polyclonal Antibody, ALEXA FLUOR® 488 Conjugated - bs-12518R-A488 from Bioss
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Argonaute 4/eIF2C4 Polyclonal Antibody, ALEXA FLUOR® 555 Conjugated - bs-12518R-A555 from Bioss
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Argonaute 4/eIF2C4 Polyclonal Antibody, ALEXA FLUOR® 647 Conjugated - bs-12518R-A647 from Bioss
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Argonaute 4/eIF2C4 Polyclonal Antibody, Cy3 Conjugated - bs-12518R-Cy3 from Bioss
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Argonaute 4/eIF2C4 Polyclonal Antibody, Cy5 Conjugated - bs-12518R-Cy5 from Bioss
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Argonaute 4/eIF2C4 Polyclonal Antibody, Cy5.5 Conjugated - bs-12518R-Cy5.5 from Bioss
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Argonaute 4/eIF2C4 Polyclonal Antibody, Cy7 Conjugated - bs-12518R-Cy7 from Bioss
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Argonaute 4/eIF2C4 Polyclonal Antibody, FITC Conjugated - bs-12518R-FITC from Bioss
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Argonaute 4/eIF2C4 Polyclonal Antibody, Biotin Conjugated - bs-12518R-Biotin from Bioss
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