ARG2

Gene Symbol ARG2
Entrez Gene 384
Alt Symbol -
Species Human
Gene Type protein-coding
Description arginase 2
Other Description L-arginine amidinohydrolase|L-arginine ureahydrolase|arginase, type II|arginase-2, mitochondrial|kidney arginase|kidney-type arginase|non-hepatic arginase|nonhepatic arginase|type II arginase
Swissprots Q6FHY8 P78540 B2R690
Accessions CBX47614 EAW80943 EAW80944 P78540 AK312484 BAG35387 AL135439 AY074489 AAL71548 BC001350 AAH01350 BC008464 AAH08464 BC029050 AAH29050 CR536550 CAG38787 D86724 BAA13158 U75667 AAB39855 U82256 AAC51664 NM_001172 NP_001163
Function May play a role in the regulation of extra-urea cycle arginine metabolism and also in down-regulation of nitric oxide synthesis. Extrahepatic arginase functions to regulate L-arginine bioavailability to NO synthase. Since NO synthase is found in the penile corpus cavernosum smooth muscle, the clitoral corpus cavernosum and the vagina, arginase II plays a role in both male and female sexual arousal. It is therefore a potential target for the treatment of male and female sexual arousal disorders. {ECO:0000269|PubMed:12859189}.
Subcellular Location Mitochondrion.
Tissue Specificity Expressed most strongly in kidney and prostate, much less strongly in the brain, skeletal muscle, placenta, lung, mammary gland, macrophage, uterus, testis and gut, but apparently not in the liver, heart and pancreas.
Top Pathways Amoebiasis, Arginine and proline metabolism, Biosynthesis of amino acids

arginase II (A-10) - sc-393496 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
arginase II (A-10): sc-393496. Western blot analysis of arginase II expression in non-transfected: sc-117752 (A) and human arginase II transfected: sc-114274 (B) 293T whole cell lysates.

arginase II (C-3) - sc-374420 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
arginase II (C-3): sc-374420. Western blot analysis of arginase II expression in non-transfected: sc-117752 (A) and human arginase II transfected: sc-114274 (B) 293T whole cell lysates.

arginase II (C-8) - sc-271443 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
arginase II (C-8): sc-271443. Western blot analysis of arginase II expression in non-transfected: sc-117752 (A) and human arginase II transfected: sc-114274 (B) 293T whole cell lysates.

arginase II (H-64) - sc-20151 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
arginase II (H-64): sc-20151. Western blot analysis of arginase II expression in rat kidney tissue extract.

arginase II (L-20) - sc-18357 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
arginase II (L-20): sc-18357. Immunofluorescence staining of methanol-fixed RAW 264.7 cells showing cytoplasmic localization.

arginase II (P-20) - sc-18360 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
arginase II (P-20): sc-18360. Immunofluorescence staining of methanol-fixed RAW 264.7 cells showing cytoplasmic localization.

Anti-Arg2 antibody - ab203071 from Abcam

Prices $359.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of formalin-fixed, paraffin-embedded Mouse liver tissue labeling Arg2 with ab203071 at 1/200 dilution followed by conjugation to the secondary antibody and DAB staining.

Anti-Arg2 antibody - ab154422 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of paraffin-embedded Human colon carcinoma tissue labeling Arg2 with ab154422 at 1/250 dilution.

Anti-Arg2 antibody - ab136092 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-Arg2 antibody (ab136092) at 1/500 dilution + HeLa cell lysate at 30 µg

Anti-Arg2 antibody [EPR9472] - ab139183 from Abcam

Prices $379.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR9472
All lanes : Anti-Arg2 antibody [EPR9472] (ab139183) at 1/1000 dilutionLane 1 : 293T cell lysateLane 2 : Jurkat cell lysateLane 3 : Caco 2 cell lysateLysates/proteins at 10 µg per lane.SecondaryHRP labelled goat anti-rabbit at 1/2000 dilution

Anti-Arg2 antibody [EPR9473] - ab137069 from Abcam

Prices $385.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR9473
Overlay histogram showing HEK293 cells stained with ab137069 (red line). The cells were fixed with 80% methanol (5 min) and then permeabilized with 0.1% PBS-Tween for 20 min. The cells were then incubated in 1x PBS / 10% normal goat serum / 0.3M glycine to block non-specific protein-protein interactions followed by the antibody (ab137069, 1/10000 dilution) for 30 min at 22°C. The secondary antibody used was Alexa Fluor® 488 goat anti-rabbit IgG (H&L) (ab150077) at 1/2000 dilution for 30 min at 22°C. Isotype control antibody (black line) was rabbit IgG (monoclonal) (0.1μg/1x106 cells) used under the same conditions. Unlabelled sample (blue line) was also used as a control. Acquisition of >5,000 events were collected using a 20mW Argon ion laser (488nm) and 525/30 bandpass filter. This antibody gave a positive signal in HEK293 cells fixed with 4% paraformaldehyde (10 min)/permeabilized with 0.1% PBS-Tween for 20 min used under the same conditions.

Anti-ARG2 / Arginase 2 Antibody (clone 3G5) - LS-C338176 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 3G5
IHC of paraffin-embedded Adenocarcinoma of Human colon tissue using anti-ARG2 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120°C for 3min).

Anti-ARG2 / Arginase 2 Antibody (aa23-354) - LS-C292935 from LifeSpan Bioscience

Prices $405.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-ARG2 / Arginase 2 Antibody (aa23-354) - LS-C292939 from LifeSpan Bioscience

Prices $415.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-ARG2 / Arginase 2 Antibody (aa23-354, Biotin) - LS-C299122 from LifeSpan Bioscience

Prices $425.00
Sizes 200 µg
Host Mouse
Clonality Monoclonal

Anti-ARG2 / Arginase 2 Antibody (aa23-354, Biotin) - LS-C299775 from LifeSpan Bioscience

Prices $435.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-ARG2 / Arginase 2 Antibody (C-Terminus) - LS-C81872 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Jurkat cell lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.

Anti-ARG2 / Arginase 2 Antibody (aa23-354) - LS-C292380 from LifeSpan Bioscience

Prices $415.00
Sizes 200 µg
Host Mouse
Clonality Monoclonal
Western blot of recombinant Arginase II / ARG2.

Anti-ARG2 / Arginase 2 Antibody (aa71-120) - LS-C135315 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
ARG2 antibody LS-C135315 Western blot of Fetal muscle lysate.

Anti-ARG2 / Arginase 2 Antibody (aa23-354, Biotin) - LS-C300188 from LifeSpan Bioscience

Prices $435.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-ARG2 / Arginase 2 Antibody (aa180-348) IHC-plus™ - LS-B10972 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
Human Prostate: Formalin-Fixed, Paraffin-Embedded (FFPE)

Anti-ARG2 / Arginase 2 Antibody (aa23-354) - LS-C292937 from LifeSpan Bioscience

Prices $425.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of recombinant Arginase II / ARG2.

Anti-ARG2 / Arginase 2 Antibody (aa23-354, Biotin) - LS-C300917 from LifeSpan Bioscience

Prices $455.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-ARG2 / Arginase 2 Antibody (aa23-354, FITC) - LS-C301431 from LifeSpan Bioscience

Prices $455.00
Sizes 200 µg
Host Mouse
Clonality Monoclonal

Anti-ARG2 / Arginase 2 Antibody (aa23-354, FITC) - LS-C302562 from LifeSpan Bioscience

Prices $465.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
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