| Gene Symbol |
SSB
|
| Entrez Gene |
6741
|
| Alt Symbol |
LARP3, La, La/SSB
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
Sjogren syndrome antigen B (autoantigen La)
|
| Other Description |
La ribonucleoprotein domain family, member 3|SS-B|SS-B/La protein|autoantigen La|la autoantigen|lupus La antigen|lupus La protein|sjoegren syndrome type B antigen
|
| Swissprots |
Q53XJ4 P05455 Q15367
|
| Accessions |
AAY14868 EAX11256 EAX11257 EAX11258 EAX11259 P05455 AB451228 BAG70042 AB451351 BAG70165 AK124811 BC001289 AAH01289 BC020818 AAH20818 BT009862 AAP88864 CD676196 D28394 BAA05760 DQ185046 ABD14426 DQ894459 ABM85385 J04205 AAA51885 M20328 AAA36577 M35261 AAA36652 M35262 AAA36654 M35263 AAA36653 S57806 S57808 X13697 CAA31985 X14684 CAA32815 X69804 NM_001294145 NP_001281074 NM_003142 NP_003133
|
| Function |
Binds to the 3' poly(U) terminus of nascent RNA polymerase III transcripts, protecting them from exonuclease digestion and facilitating their folding and maturation. {ECO:0000269|PubMed:2470590, ECO:0000269|PubMed:3192525}.
|
| Subcellular Location |
Nucleus {ECO:0000305}.
|
| Top Pathways |
Systemic lupus erythematosus
|
![Western Blot: SSB Overexpression Lysate (Adult Normal) [NBL1-16464] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for SSB.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/7751_SSB%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-16464-img0002.jpg)