PLSCR3

Gene Symbol	PLSCR3
Entrez Gene	57048
Alt Symbol	-
Species	Human
Gene Type	protein-coding
Description	phospholipid scramblase 3
Other Description	PL scramblase 3|ca(2+)-dependent phospholipid scramblase 3
Swissprots	Q96F13 Q9NRY6 Q567U0 A8K252 Q8NBW6
Accessions	CAF86478 EAW90198 EAW90200 EAW90202 Q9NRY6 AF159442 AAF91083 AF289602 AAL55786 AK075188 BAC11458 AK098229 AK124006 AK314643 BAG37205 BC011735 AAH11735 BC028080 BC093026 AAH93026 BG830095 CX785894 DQ893413 ABM84339 DQ896733 ABM87732 NM_001201576 NP_001188505 NM_020360 NP_065093
Function	May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. May play a central role in the initiation of fibrin clot formation, in the activation of mast cells and in the recognition of apoptotic and injured cells by the reticuloendothelial system. Seems to play a role in apoptosis, through translocation of cardiolipin from the inner to the outer mitochondrial membrane which promotes BID recruitment and enhances tBid-induced mitochondrial damages. {ECO:0000269|PubMed:17226776}.
Subcellular Location	Mitochondrion membrane {ECO:0000269|PubMed:17226776}; Single-pass type II membrane protein {ECO:0000269|PubMed:17226776}.
Tissue Specificity	Expressed in heart, placenta, lung, liver, skeletal muscle, kidney, pancreas, spleen, thymus, prostate, uterus, small intestine and peripheral blood lymphocytes. Not detected in testis, brain and liver.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

PLSCR3 CRISPR/Cas9 KO Plasmid (h) - sc-408265 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

PLSCR3 HDR Plasmid (h) - sc-408265-HDR from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

PLSCR3 Double Nickase Plasmid (h) - sc-408265-NIC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

PLSCR3 Double Nickase Plasmid (h2) - sc-408265-NIC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

PLSCR3 CRISPR Activation Plasmid (h) - sc-408265-ACT from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

PLSCR3 CRISPR Activation Plasmid (h2) - sc-408265-ACT-2 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

PLSCR3 Lentiviral Activation Particles (h) - sc-408265-LAC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

PLSCR3 Lentiviral Activation Particles (h2) - sc-408265-LAC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

PLSCR3 siRNA (h) - sc-62828 from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

PLSCR3 shRNA Plasmid (h) - sc-62828-SH from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

PLSCR3 shRNA (h) Lentiviral Particles - sc-62828-V from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

PLSCR3 RNAi - H00057048-R01V from Novus Biologicals Category siRNA Prices $399.00 Sizes 20 nmol Species Reactivities Human

PLSCR3 RNAi - H00057048-R01 from Novus Biologicals Category siRNA Prices $399.00 Sizes 20 nmol Species Reactivities Human

MISSION® esiRNA - EHU088251 from Sigma-Aldrich Category siRNA Prices $250.00 Sizes 50 µg

MISSION® esiRNA - EHU096231 from Sigma-Aldrich Category siRNA Prices $140.00, $250.00 Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN17002 from Sigma-Aldrich Category ZFN Kit Prices $4,999.00 Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND17002 from Sigma-Aldrich Category ZFN Kit Prices $3,999.00 Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR05473 from Sigma-Aldrich Category miRNA

PLSCR3 siRNA (Human) - CRJ1300 from Cohesion Biosciences Category siRNA Prices $340.00, $510.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

PLSCR3 shRNA Plasmid (Human) - CHJ1300 from Cohesion Biosciences Category siRNA Prices $500.00, $750.00 Sizes 150 µg, 300 µg Species Reactivities Human

PLSCR3 miRNA 3'UTR clone - MiUTR3H-09343 from Creative biogene Species Reactivities Human

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