PLSCR3

Gene Symbol PLSCR3
Entrez Gene 57048
Alt Symbol -
Species Human
Gene Type protein-coding
Description phospholipid scramblase 3
Other Description PL scramblase 3|ca(2+)-dependent phospholipid scramblase 3
Swissprots Q96F13 Q9NRY6 Q567U0 A8K252 Q8NBW6
Accessions CAF86478 EAW90198 EAW90200 EAW90202 Q9NRY6 AF159442 AAF91083 AF289602 AAL55786 AK075188 BAC11458 AK098229 AK124006 AK314643 BAG37205 BC011735 AAH11735 BC028080 BC093026 AAH93026 BG830095 CX785894 DQ893413 ABM84339 DQ896733 ABM87732 NM_001201576 NP_001188505 NM_020360 NP_065093
Function May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. May play a central role in the initiation of fibrin clot formation, in the activation of mast cells and in the recognition of apoptotic and injured cells by the reticuloendothelial system. Seems to play a role in apoptosis, through translocation of cardiolipin from the inner to the outer mitochondrial membrane which promotes BID recruitment and enhances tBid-induced mitochondrial damages. {ECO:0000269|PubMed:17226776}.
Subcellular Location Mitochondrion membrane {ECO:0000269|PubMed:17226776}; Single-pass type II membrane protein {ECO:0000269|PubMed:17226776}.
Tissue Specificity Expressed in heart, placenta, lung, liver, skeletal muscle, kidney, pancreas, spleen, thymus, prostate, uterus, small intestine and peripheral blood lymphocytes. Not detected in testis, brain and liver.

PLSCR3 (N-15) - sc-68122 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
PLSCR3 (N-15): sc-68122. Western blot analysis of PLSCR3 expression in adipose-treated 3T3-L1 (A) and Sol8 (B) whole cell lysates and mouse lung tissue extract (C).

PLSCR3 (H-72) - sc-135240 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
PLSCR3 (H-72): sc-135240. Western blot analysis of PLSCR3 expression in mouse lung tissue extract.

PLSCR3 (T-13) - sc-68123 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

PLSCR3 (SQ-9) - sc-100808 from Santa Cruz Biotechnology

Prices $295.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal
PLSCR3 (SQ-9): sc-100808. Western blot analysis of PLSCR3 expression in HL-60 whole cell lysate.

Anti-PLSCR3 antibody - ab57554 from Abcam

Prices $380.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
ab57554 staining PLSCR3 in RAW264.7 cells from Mouse macrophages by ICC/IF (Immunocytochemistry/immunofluorescence). Cells were fixed with paraformaldehyde, permeabilized with Triton 0.1% + 2% BSA in PBS and blocked with 2% BSA for 60 minutes at 24°C. Samples were incubated with primary antibody (1/100n PBS + 2%BSA) for 16 hours at 4°C. An  Alexa Fluor®488-conjugated Goat anti-mouse polyclonal(1/1000) was used as the secondary antibody.See Abreview

Anti-PLSCR3 antibody - ab99169 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-PLSCR3 antibody (ab99169) at 1 µg/ml + placenta lysate at 10 µg

Anti-PLSCR3 antibody - ab172748 from Abcam

Prices $370.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
All lanes : Anti-PLSCR3 antibody (ab172748) at 1/500 dilutionLane 1 : PLSCR3 transfected 293T cell lysateLane 2 : Nom-transfected 293T cell lysateLysates/proteins at 15 µl per lane.

Anti-PLSCR3 antibody - ab22215 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-PLSCR3 antibody [EPR9242] - ab137128 from Abcam

Prices $357.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR9242
All lanes : Anti-PLSCR3 antibody [EPR9242] (ab137128) at 1/1000 dilutionLane 1 : Human fetal lung lysateLane 2 : BxPC 3 lysateLysates/proteins at 10 µg per lane.SecondaryHRP labelled goat anti-rabbit at 1/2000 dilution

Anti-PLSCR3 Antibody (aa1-296, Azide-free) - LS-C328275 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal

Anti-PLSCR3 Antibody (aa215-264) - LS-C112050 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
PLSCR3 antibody LS-C112050 Western blot of Placenta lysate.

PLSCR3 Antibody - NBP1-52866 from Novus Biologicals

Prices $139.00, $329.00
Sizes 20 µl, 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: PLSCR3 Antibody [NBP1-52866] - Analysis of PLSCR3 in mouse lung tissues using PLSCR3 antibody. Tissues were untreated or treated with 100 ng/ml LPS. Image from verified customer review.

PLSCR3 Antibody - H00057048-D01P from Novus Biologicals

Prices $399.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western Blot: PLSCR3 Antibody [H00057048-D01P] - Analysis of PLSCR3 expression in mouse brain.

PLSCR3 Antibody (2C8) - H00057048-M09 from Novus Biologicals

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 2C8
Western Blot: PLSCR3 Antibody (2C8) [H00057048-M09] - Analysis of PLSCR3 expression in HL-60 (Cat # L014V1).

PLSCR3 Antibody - NBP1-33072 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

PLSCR3 Antibody (1B5) - H00057048-M08 from Novus Biologicals

Prices $349.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 1B5
Western Blot: PLSCR3 Antibody (1B5) [H00057048-M08] - PLSCR3 monoclonal antibody (M08), clone 1B5. Western Blot analysis of PLSCR3 expression in PC-12 ( Cat # L012V1 ).

PLSCR3 Antibody (4B5) - H00057048-M02 from Novus Biologicals

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 4B5
Western Blot: PLSCR3 Antibody (4B5) [H00057048-M02] - PLSCR3 monoclonal antibody (M02), clone 4B5. Analysis of PLSCR3 expression in PC-12.

PLSCR3 Antibody (4F5) - H00057048-M04 from Novus Biologicals

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 4F5
Western Blot: PLSCR3 Antibody (4F5) [H00057048-M04] - Analysis of PLSCR3 expression in PC-12 (Cat # L012V1).

PLSCR3 Antibody - H00057048-D01 from Novus Biologicals

Prices $399.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

PLSCR3 Antibody - H00057048-B01 from Novus Biologicals

Prices $349.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
Western Blot: PLSCR3 Antibody [H00057048-B01] - analysis of PLSCR3 expression in transfected 293T cell line by PLSCR3 MaxPab polyclonal antibody (B01). Lane 1: PLSCR3 transfected lysate (31.70 KDa). Lane 2: Non-transfected lysate.

PLSCR3 Antibody (4D11) - H00057048-M10 from Novus Biologicals

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 4D11
Western Blot: PLSCR3 Antibody (4D11) [H00057048-M10] - Analysis of PLSCR3 expression in transfected 293T cell line by PLSCR3 monoclonal antibody (M10), clone 4D11. Lane 1: PLSCR3 transfected lysatE (31.7 KDa). Lane 2: Non-transfected lysate.

PLSCR3 Antibody - H00057048-A01 from Novus Biologicals

Prices $269.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal

PLSCR3 Polyclonal Antibody - bs-7099R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Monoclonal Anti-PLSCR3 antibody produced in mouse - SAB1405202 from Sigma-Aldrich

Prices $347.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 4B5
<B>Immunoblotting</B><BR/>Monoclonal Anti-PLSCR3: <B>Cat. No. SAB1405202</B>: Antibody concentration: 1-5 μg/mL. Specific band of ~31.7 kDa using PC~12 lysate.

Monoclonal Anti-PLSCR3 antibody produced in mouse - SAB1401778 from Sigma-Aldrich

Prices $347.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 4D11
<B>Immunoblotting</B><BR/>Monoclonal Anti-PLSCR3, antibody produced in mouse, clone 4D11, purified immunoglobulin: <B>Cat. No. SAB1401778</B>: Antibody concentration: 1.0 μg/mL. Specific band of ~36.23 kDa using immunogen protein lysate.
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