NEU4

Gene Symbol NEU4
Entrez Gene 129807
Alt Symbol -
Species Human
Gene Type protein-coding
Description sialidase 4
Other Description N-acetyl-alpha-neuraminidase 4|neuraminidase 4|sialidase-4
Swissprots Q96D64 J3KNJ5 A8K056 Q8WWR8
Accessions AAX82022 EAW71294 EAW71295 EAW71296 EAW71297 Q8WWR8 AJ277883 CAC81904 AK025617 AK091038 BAG52266 AK096992 AK289421 BAF82110 AK290076 BAF82765 AK298403 BAH12778 AK300969 BAH13385 AY203952 AAP34475 BC012899 AAH12899 BC063465 BC067780 BC105974 AAI05975 BC117214 AAI17215 BQ651855 DB173219 DC412650 HQ258276 ADR83030 NM_001167599 NP_001161071 NM_001167600 NP_001161072 NM_001167601 NP_001161073 NM_001167602 NP_001161074 NM_080741 NP_542779
Function May function in lysosomal catabolism of sialylated glycoconjugates. Has sialidase activity towards synthetic substrates, such as 2'-(4-methylumbelliferyl)-alpha-D-N- acetylneuraminic acid (4-MU-NANA or 4MU-NeuAc). Has a broad substrate specificity being active on glycoproteins, oligosaccharides and sialylated glycolipids. {ECO:0000269|PubMed:14962670, ECO:0000269|PubMed:15213228}.
Subcellular Location Isoform 1: Membrane; Peripheral membrane protein.
Tissue Specificity Ubiquitous with higher expression in heart, skeletal muscle, liver and placenta. {ECO:0000269|PubMed:14962670}.
Top Pathways Sphingolipid metabolism, Other glycan degradation

Neu4 (L-15) - sc-161126 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Neu4 (N-14) - sc-161127 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Neu4 (H-88) - sc-366571 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

Anti-NEU4 antibody - ab86539 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-NEU4 antibody (ab86539) at 1 µg/ml (in 5% skim milk / PBS buffer) + 293T cell lysate at 10 µgSecondaryHRP conjugated anti-Rabbit IgG at 1/50000 dilution

Anti-NEU4 antibody - ab107258 from Abcam

Prices $359.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-NEU4 antibody (ab107258) at 1/100 dilution + Mouse liver tissue lysate at 35 µg

Anti-NEU4 Antibody (aa423-452, AP) - LS-C237972 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-NEU4 Antibody (aa423-452, APC) - LS-C237973 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-NEU4 Antibody (aa423-452, Biotin) - LS-C237974 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-NEU4 Antibody (aa423-452, FITC) - LS-C237976 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-NEU4 Antibody (aa423-452, PE) - LS-C237977 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-NEU4 Antibody (aa423-452, Azide-free, HRP) - LS-C248900 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-NEU4 Antibody (aa430-461) - LS-C323303 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-NEU4 Antibody - LS-C155638 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Sample (30 ug of whole cell lysate) A: 293T B: A431 10% SDS PAGE NEU4 antibody diluted at 1:500

Anti-NEU4 Antibody (aa107-156) - LS-C102432 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
NEU4 antibody LS-C102432 Western blot of 293T cell lysate.

Anti-NEU4 Antibody (aa423-452) - LS-C164834 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
NEU4 antibody immunohistochemistry of formalin-fixed and paraffin-embedded human hepatocarcinoma followed by peroxidase-conjugated secondary antibody and DAB staining.

NEU4 Antibody - NBP2-32682 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: NEU4 Antibody [NBP2-32682] - Lane 1: Marker [kDa] 230, 130, 95, 72, 56, 36, 28, 17, 11. Lane 2: Human cell line RT-4. Lane 3: Human cell line U-251MG sp

NEU4 Antibody - NBP1-86278 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: NEU4 Antibody [NBP1-86278] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10. Lane 2: Negative control (vector only transfected HEK293T lysate). Lane 3: Over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (3.1 kDa) in mammalian HEK293T cells).

NEU4 Antibody - NBP1-56703 from Novus Biologicals

Prices $139.00, $329.00
Sizes 20 µl, 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: NEU4 Antibody [NBP1-56703] - Titration: 0.2-1 ug/ml, Positive Control: 293T cell lysate.

NEU4 Antibody - NBP2-19517 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: NEU4 Antibody [NBP2-19517] - Sample (30 ug of whole cell lysate) A: 293T B: A431 10% SDS PAGE gel, diluted at 1:500.

Anti-NEU4 antibody produced in rabbit - HPA037394 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-NEU4: <B>Cat. No. HPA037394</B>: Immunohistochemical staining of Human colon shows strong cytoplasmic positivity in endocrine cells.

Anti-NEU4 antibody produced in rabbit - SAB2101571 from Sigma-Aldrich

Prices $347.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-NEU4: <B>Cat. No.SAB2101571</B>: NEU4 in 293T cell lysate with NEU4 antibody at 1.0 μg/mL.

Anti-NEU4 antibody produced in rabbit - HPA037395 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-NEU4: <B>Cat. No. HPA037395</B>: Immunohistochemical staining of human testis shows strong cytoplasmic positivity in cells in seminiferus ducts.

Anti-NEU4 (23-35) antibody produced in rabbit - SAB1103340 from Sigma-Aldrich

Prices $298.50
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Lysate of HEK-293T cells overexpressing human NEU4 was separated on SDS-PAGE, blotted with Anti-NEU4 (23-35) (<B>Cat. No. SAB1103340</B>) and developed using Goat Anti-Rabbit IgG-Peroxidase (<B>Cat. No. A0545</B>) and a chemiluminescent substrate.<BR/><B>Lanes</B><BR/>1. Antibody dilution 1:250

NEU4 antibody - N-terminal region (ARP52522_P050) - ARP52522_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

NEU4 Antibody - C-terminal region (OAAB00394) - OAAB00394 from Aviva Systems Biology

Prices $289.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
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