NEU4

Gene Symbol NEU4
Entrez Gene 129807
Alt Symbol -
Species Human
Gene Type protein-coding
Description sialidase 4
Other Description N-acetyl-alpha-neuraminidase 4|neuraminidase 4|sialidase-4
Swissprots Q96D64 J3KNJ5 A8K056 Q8WWR8
Accessions AAX82022 EAW71294 EAW71295 EAW71296 EAW71297 Q8WWR8 AJ277883 CAC81904 AK025617 AK091038 BAG52266 AK096992 AK289421 BAF82110 AK290076 BAF82765 AK298403 BAH12778 AK300969 BAH13385 AY203952 AAP34475 BC012899 AAH12899 BC063465 BC067780 BC105974 AAI05975 BC117214 AAI17215 BQ651855 DB173219 DC412650 HQ258276 ADR83030 NM_001167599 NP_001161071 NM_001167600 NP_001161072 NM_001167601 NP_001161073 NM_001167602 NP_001161074 NM_080741 NP_542779
Function May function in lysosomal catabolism of sialylated glycoconjugates. Has sialidase activity towards synthetic substrates, such as 2'-(4-methylumbelliferyl)-alpha-D-N- acetylneuraminic acid (4-MU-NANA or 4MU-NeuAc). Has a broad substrate specificity being active on glycoproteins, oligosaccharides and sialylated glycolipids. {ECO:0000269|PubMed:14962670, ECO:0000269|PubMed:15213228}.
Subcellular Location Isoform 1: Membrane; Peripheral membrane protein.
Tissue Specificity Ubiquitous with higher expression in heart, skeletal muscle, liver and placenta. {ECO:0000269|PubMed:14962670}.
Top Pathways Sphingolipid metabolism, Other glycan degradation

Neu4 CRISPR/Cas9 KO Plasmid (h) - sc-406284 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Neu4 HDR Plasmid (h) - sc-406284-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Neu4 Double Nickase Plasmid (h) - sc-406284-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Neu4 Double Nickase Plasmid (h2) - sc-406284-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Neu4 CRISPR Activation Plasmid (h) - sc-406284-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Neu4 CRISPR Activation Plasmid (h2) - sc-406284-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Neu4 Lentiviral Activation Particles (h) - sc-406284-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Neu4 Lentiviral Activation Particles (h2) - sc-406284-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Neu4 siRNA (h) - sc-94619 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Neu4 shRNA Plasmid (h) - sc-94619-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Neu4 shRNA (h) Lentiviral Particles - sc-94619-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CompoZr® Knockout ZFN Kit - CKOZFN15218 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND15218 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

NEU4 siRNA (Human) - CRJ5011 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human NEU4 (NM_080741.2) - SHH351480 from Creative biogene

Category siRNA
Species Reactivities Human

NEU4 shRNA Plasmid (Human) - CHJ5011 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

NEU4 miRNA 3'UTR clone - MiUTR4H-TG11834 from Creative biogene

Species Reactivities Human
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