PCSK6

Gene Symbol	PCSK6
Entrez Gene	5046
Alt Symbol	PACE4, SPC4
Species	Human
Gene Type	protein-coding
Description	proprotein convertase subtilisin/kexin type 6
Other Description	paired basic amino acid cleaving enzyme 4|paired basic amino acid cleaving system 4|subtilisin-like proprotein convertase 4|subtilisin/kexin-like protease PACE4
Swissprots	Q9UEJ2 Q9UEG7 Q9UEJ8 Q9Y4H0 P29122 Q9UEJ1 Q9UEJ7 Q9UEJ9 Q9Y4G9 Q15099 Q9Y4H1 Q15100
Accessions	BAA21620 BAA21621 BAA21622 BAA21623 BAA21624 BAA21625 BAA21626 BAA21627 EAX02301 EAX02302 EAX02303 EAX02304 EAX02305 EAX02306 EAX02307 EAX02308 EAX02309 EAX02310 EAX02311 P29122 AB208955 BAD92192 AI478762 AL545278 AM491522 CAM33226 AW137040 BC043562 BU732171 BX428035 BX649058 D28513 BAA05871 D87993 BAA21791 D87994 BAA21792 D87995 BAA21793 DB143095 HY122769 HY205376 LN714797 CEK43043 M80482 AAA59998 NM_001291309 NP_001278238 NM_002570 NP_002561 NM_138319 NP_612192 NM_138322 NP_612195 NM_138323 NP_612196 NM_138324 NP_612197 NM_138325 NP_612198 NM_138320 NM_138321
Function	Likely to represent an endoprotease activity within the constitutive secretory pathway, with unique restricted distribution in both neuroendocrine and non-neuroendocrine tissues and capable of cleavage at the RX(K/R)R consensus motif.
Subcellular Location	Isoform PACE4B: Secreted.
Tissue Specificity	Each PACE4 isoform exhibits a unique restricted distribution. Isoform PACE4A-I is expressed in heart, brain, placenta, lung, skeletal muscle, kidney, pancreas, but at comparatively higher levels in the liver. Isoform PACE4A-II is at least expressed in placenta. Isoform PACE4B was only found in the embryonic kidney cell line from which it was isolated. Isoform PACE4C and isoform PACE4D are expressed in placenta. Isoform PACE4E-I is expressed in cerebellum, placenta and pituitary. Isoform PACE4E-II is at least present in cerebellum.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human PACE4 protein fragment - ab114961 from Abcam Category Protein Source Wheat germ Species Human

PACE4 / PCSK6 Antibody Blocking Peptide - LS-E3630 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

PACE4 / PCSK6 Antibody Blocking Peptide - LS-E29407 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

PACE4 / PCSK6 Antibody Blocking Peptide - LS-E11204 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

PACE4 / PCSK6 Antibody Blocking Peptide - LS-E26893 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

PACE4 / PCSK6 Antibody Blocking Peptide - LS-E26859 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

PACE4 / PCSK6 Antibody Blocking Peptide - LS-E29287 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

PACE4 / PCSK6 Antibody Blocking Peptide - LS-E29292 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

PACE4 Partial Recombinant Protein - H00005046-Q01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

PCSK6-Antibody-C-term-Blocking-Peptide - BP14833b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

PACE4 blocking peptide - GTX88546-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human, Mouse, Rat

PACE4 blocking peptide - GTX88576-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human

PCSK6 Immunizing peptide - orb17335 from Biorbyt Category Peptide Prices $247.00 Sizes 100 μg Species Human, Mouse, Rat

PCSK6 Blocking Peptide - 33R-6937 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

PCSK6 Blocking Peptide - 33R-4225 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

PACE4 Peptide - AC21-1693-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

PACE4 Peptide - AC21-1726-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

PCSK6 / PACE4 - H00005046-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

PCSK6 / PACE4 - H00005046-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

PACE4 Peptide - 46-742P from ProSci Category Peptide

PCSK6 Peptide - 46-729P from ProSci Category Peptide Species Human

Recombinant Human PCSK6 - PCSK6-30177TH from Creative Biomart Category Protein Source Wheat germ

Recombinant Human Proprotein convertase subtilisin/kexin type 6(PCSK6) ,partial - CSB-YP017645HU CSB-EP017645HU CSB-BP017645HU CSB-MP017645HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

Proprotein convertase subtilisin/kexin type 6 (PCSK6), partial, Recombinant Protein - MBS950934 from MyBioSource Category Protein Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

PACE4, Peptide - MBS425967 from MyBioSource Category Peptide Prices $175.00 Sizes 100 µg Species Human, Mouse, Rat

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