Gene Symbol | GPRC5B |
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Entrez Gene | 51704 |
Alt Symbol | RAIG-2, RAIG2 |
Species | Human |
Gene Type | protein-coding |
Description | G protein-coupled receptor, class C, group 5, member B |
Other Description | G protein-coupled receptor, family C, group 1, member B|G-protein coupled receptor family C group 5 member B|retinoic acid responsive gene protein|retinoic acid-induced gene 2 protein |
Swissprots | Q9NZH0 D2DFB0 Q8NBZ8 O75205 |
Accessions | AAC27544 EAW50302 EAW50303 EAW50304 EAW50305 Q9NZH0 AF181862 AAF05331 AF202640 AAF67321 AJ276101 CAC00632 AK075119 BAC11414 AK294680 BAH11846 AK295204 BAH12012 AK296754 BAH12426 AK302838 BAH13817 AK315989 BAH14360 AL137684 BC034467 AAH34467 BI462652 DA141861 DC344063 DQ890851 ABM81777 DQ894006 ABM84932 FJ529380 ACU30030 XM_006721051 XP_006721114 XM_006721052 XP_006721115 NM_001304771 NP_001291700 NM_016235 NP_057319 |
Function | Unknown. This retinoic acid-inducible G-protein coupled receptor provide evidence for a possible interaction between retinoid and G-protein signaling pathways. |
Subcellular Location | Cell membrane {ECO:0000269|PubMed:10945465}; Multi-pass membrane protein {ECO:0000269|PubMed:10945465}. Cytoplasmic vesicle membrane {ECO:0000269|PubMed:10945465}; Multi- pass membrane protein {ECO:0000269|PubMed:10945465}. Note=Localized in the plasma membrane and perinuclear vesicles. |
Tissue Specificity | Expression is high in kidney, pancreas, and testis, medium in brain, heart, prostate, small intestine, and spleen, low in liver, placenta, skeletal muscle, colon, ovary, and thymus, and not detectable in lung and peripheral leukocyte. According to PubMed:10945465, highly expressed in most brain areas examined, with the highest levels observed in corpus callosum, caudate nucleus, putamen, substantia nigra, thalamus, hippocampus, and spinal chord as well as in dorsal root ganglia (DRG). In the periphery, expression levels are relatively low, compared to the CNS, with the strongest expression detected in pancreas, testis, uterus, and stomach. {ECO:0000269|PubMed:10783259, ECO:0000269|PubMed:10945465}. |
GPRC5B (T-16) - sc-68093 from Santa Cruz Biotechnology
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GPRC5B (E-17) - sc-68091 from Santa Cruz Biotechnology
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GPRC5B (C-19) - sc-68090 from Santa Cruz Biotechnology
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GPRC5B (H-64) - sc-135260 from Santa Cruz Biotechnology
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GPRC5B (N-16) - sc-68092 from Santa Cruz Biotechnology
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Anti-GPCR GPRC5B antibody - ab75427 from Abcam
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Anti-GPCR GPRC5B antibody - ab129554 from Abcam
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Anti-GPCR GPRC5B antibody [EPR10190] - ab173531 from Abcam
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Anti-GPCR GPRC5B antibody [EPR10191] - ab176326 from Abcam
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Anti-GPCR GPRC5B antibody - C-terminal - ab189043 from Abcam
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Anti-RAIG2 / GPRC5B Antibody (aa293-321, AP) - LS-C214911 from LifeSpan Bioscience
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Anti-RAIG2 / GPRC5B Antibody (aa293-321, APC) - LS-C214912 from LifeSpan Bioscience
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Anti-RAIG2 / GPRC5B Antibody (aa61-110) IHC-plus⢠- LS-B12014 from LifeSpan Bioscience
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Anti-RAIG2 / GPRC5B Antibody (aa293-321, Biotin) - LS-C214913 from LifeSpan Bioscience
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Anti-RAIG2 / GPRC5B Antibody (aa293-321, FITC) - LS-C214914 from LifeSpan Bioscience
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Anti-RAIG2 / GPRC5B Antibody (C-Terminus) IHC-plus⢠- LS-A412 from LifeSpan Bioscience
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Anti-RAIG2 / GPRC5B Antibody (aa293-321, Azide-free, HRP) - LS-C214916 from LifeSpan Bioscience
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Anti-RAIG2 / GPRC5B Antibody (aa293-321, PE) - LS-C214917 from LifeSpan Bioscience
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Anti-RAIG2 / GPRC5B Antibody (aa292-321) - LS-C321768 from LifeSpan Bioscience
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Anti-RAIG2 / GPRC5B Antibody (C-Terminus) IHC-plus⢠- LS-A413 from LifeSpan Bioscience
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Anti-RAIG2 / GPRC5B Antibody (N-Terminus) IHC-plus⢠- LS-A4084 from LifeSpan Bioscience
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Anti-RAIG2 / GPRC5B Antibody (aa293-321) - LS-C166646 from LifeSpan Bioscience
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Anti-RAIG2 / GPRC5B Antibody (aa61-110) - LS-C120704 from LifeSpan Bioscience
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Anti-RAIG2 / GPRC5B Antibody (C-Terminus) IHC-plus⢠- LS-A4088 from LifeSpan Bioscience
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Anti-RAIG2 / GPRC5B Antibody (C-Terminus) IHC-plus⢠- LS-A414 from LifeSpan Bioscience
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