Gene Symbol | GPRC5B |
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Entrez Gene | 51704 |
Alt Symbol | RAIG-2, RAIG2 |
Species | Human |
Gene Type | protein-coding |
Description | G protein-coupled receptor, class C, group 5, member B |
Other Description | G protein-coupled receptor, family C, group 1, member B|G-protein coupled receptor family C group 5 member B|retinoic acid responsive gene protein|retinoic acid-induced gene 2 protein |
Swissprots | Q9NZH0 D2DFB0 Q8NBZ8 O75205 |
Accessions | AAC27544 EAW50302 EAW50303 EAW50304 EAW50305 Q9NZH0 AF181862 AAF05331 AF202640 AAF67321 AJ276101 CAC00632 AK075119 BAC11414 AK294680 BAH11846 AK295204 BAH12012 AK296754 BAH12426 AK302838 BAH13817 AK315989 BAH14360 AL137684 BC034467 AAH34467 BI462652 DA141861 DC344063 DQ890851 ABM81777 DQ894006 ABM84932 FJ529380 ACU30030 XM_006721051 XP_006721114 XM_006721052 XP_006721115 NM_001304771 NP_001291700 NM_016235 NP_057319 |
Function | Unknown. This retinoic acid-inducible G-protein coupled receptor provide evidence for a possible interaction between retinoid and G-protein signaling pathways. |
Subcellular Location | Cell membrane {ECO:0000269|PubMed:10945465}; Multi-pass membrane protein {ECO:0000269|PubMed:10945465}. Cytoplasmic vesicle membrane {ECO:0000269|PubMed:10945465}; Multi- pass membrane protein {ECO:0000269|PubMed:10945465}. Note=Localized in the plasma membrane and perinuclear vesicles. |
Tissue Specificity | Expression is high in kidney, pancreas, and testis, medium in brain, heart, prostate, small intestine, and spleen, low in liver, placenta, skeletal muscle, colon, ovary, and thymus, and not detectable in lung and peripheral leukocyte. According to PubMed:10945465, highly expressed in most brain areas examined, with the highest levels observed in corpus callosum, caudate nucleus, putamen, substantia nigra, thalamus, hippocampus, and spinal chord as well as in dorsal root ganglia (DRG). In the periphery, expression levels are relatively low, compared to the CNS, with the strongest expression detected in pancreas, testis, uterus, and stomach. {ECO:0000269|PubMed:10783259, ECO:0000269|PubMed:10945465}. |
Human GPCR GPRC5B full length protein - ab162642 from Abcam
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Human GPCR GPRC5B protein fragment - ab162643 from Abcam
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RAIG2 / GPRC5B Antibody Blocking Peptide - LS-E4188 from LifeSpan Bioscience
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RAIG2 / GPRC5B Antibody Blocking Peptide - LS-E28883 from LifeSpan Bioscience
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RAIG2 / GPRC5B Antibody Blocking Peptide - LS-E28884 from LifeSpan Bioscience
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RAIG2 / GPRC5B Antibody Blocking Peptide - LS-E28890 from LifeSpan Bioscience
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RAIG2 / GPRC5B Antibody Blocking Peptide - LS-E28894 from LifeSpan Bioscience
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RAIG2 / GPRC5B Blocking Peptide - LS-E28896 from LifeSpan Bioscience
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RAIG2 / GPRC5B Antibody Blocking Peptide - LS-E21891 from LifeSpan Bioscience
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RAIG2 / GPRC5B Antibody Blocking Peptide - LS-E35706 from LifeSpan Bioscience
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Recombinant Human GPRC5B Protein - H00051704-P01 from Novus Biologicals
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Recombinant Human GPRC5B Protein - H00051704-Q01 from Novus Biologicals
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Recombinant Human GPRC5B Protein - H00051704-G01 from Novus Biologicals
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GPRC5B-Antibody-C-term-Blocking-Peptide - BP16444b from Abgent, a WuXi AppTec company
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GPRC5B Blocking Peptide - 33R-1582 from Fitzgerald
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GPRC5B Blocking Peptide - abx063875 from Abbexa
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GPRC5B / RAIG2 - H00051704-G01 from Acris Antibodies
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GPRC5B / RAIG2 - H00051704-P01-10 from Acris Antibodies
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GPRC5B / RAIG2 - H00051704-P01-25 from Acris Antibodies
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GPRC5B / RAIG2 - H00051704-Q01-10 from Acris Antibodies
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GPRC5B / RAIG2 - H00051704-Q01-25 from Acris Antibodies
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GPRC5B fusion protein - ag8085 from Proteintech Group
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GPRC5B fusion protein - ag4908 from Proteintech Group
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GPRC5B Blocking Peptide - CBP2681 from Cohesion Biosciences
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GPRC5B fusion protein - Ag25225 from Proteintech Group
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