PNPLA1

Gene Symbol PNPLA1
Entrez Gene 285848
Alt Symbol ARCI10, dJ50J22.1
Species Human
Gene Type protein-coding
Description patatin-like phospholipase domain containing 1
Other Description patatin-like phospholipase domain-containing protein 1
Swissprots Q3SY96 A3RMU3 Q3SY95 Q5R3L2 J3JS20 Q8N8W4 Q2A6N1
Accessions EAX03883 Q8N8W4 AK096074 BAC04697 AM182887 CAJ58679 BC103905 AAI03906 BC103906 AAI03907 BC103907 AAI03908 FJ457781 ACJ70710 XM_011514519 XP_011512821 XM_011514520 XP_011512822 XM_011514521 XP_011512823 XM_011514522 XP_011512824 XM_011514523 XP_011512825 XM_011514524 XP_011512826 XM_011514525 XP_011512827 XM_011514526 XP_011512828 NM_001145716 NP_001139188 NM_001145717 NP_001139189 NM_173676 NP_775947 NM_001039725
Function Lipid hydrolase. Important in the formation of the epidermal lipid barrier. Plays a role in glycerophospholipid metabolism. {ECO:0000269|PubMed:22246504}.
Subcellular Location Cytoplasm {ECO:0000269|PubMed:22246504}. Note=Clearly distributed in the cytoplasm of keratinocytes.
Tissue Specificity Expressed in the digestive system. Expressed in the epidermis of skin keratinocytes. Strongly expressed in the granular layer. Expressed in the upper epidermis and eccrine sweat glands of the dermis and in the region of keratin filament bundles, which is more pronounced in upper epidermal layers and in the lower cornified layers. {ECO:0000269|PubMed:16799181, ECO:0000269|PubMed:22246504}.

PNPLA1 (Y-15) - sc-49708 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
PNPLA1 (Y-15): sc-49708. Immunoperoxidase staining of formalin fixed, paraffin-embedded human duodenum tissue showing cytoplasmic staining of glandular cells.

Anti-PNPLA1 antibody - ab102069 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-PNPLA1 antibody (ab102069) at 1 µg/ml + COLO205 cell lysate at 10 µg

Anti-PNPLA1 antibody - ab169412 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
All lanes : Anti-PNPLA1 antibody (ab169412) at 1 µg/mlLane 1 : PNPLA1 transfected 293T cell lysateLane 2 : Non-transfected 293T cell lysateLysates/proteins at 15 µl per lane.

Anti-PNPLA1 antibody - N-terminal - ab171652 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-PNPLA1 antibody - N-terminal (ab171652) at 1/100 dilution + 293 cell line lysate at 35 µg

Anti-PNPLA1 Antibody (aa1-30, AP) - LS-C239217 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PNPLA1 Antibody (aa1-30, APC) - LS-C239219 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PNPLA1 Antibody (aa1-30, Biotin) - LS-C239220 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PNPLA1 Antibody (aa1-30, FITC) - LS-C239221 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PNPLA1 Antibody (aa1-30, PE) - LS-C239222 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PNPLA1 Antibody (aa1-30, Azide-free, HRP) - LS-C248507 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PNPLA1 Antibody (aa1-30) - LS-C324139 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PNPLA1 Antibody (aa418-467) - LS-C116362 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
PNPLA1 antibody LS-C116362 Western blot of COLO205 cell lysate.

Anti-PNPLA1 Antibody (aa1-30) - LS-C158690 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
PNPLA1 Antibody western blot of 293 cell line lysates (35 ug/lane). The PNPLA1 antibody detected the PNPLA1 protein (arrow).

PNPLA1 Antibody - NBP1-85172 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunocytochemistry/Immunofluorescence: PNPLA1 Antibody [NBP1-85172] - Staining of human cell line U-2 OS shows positivity in cytoskeleton (intermediate filaments).

PNPLA1 Antibody - NBP1-53193 from Novus Biologicals

Prices $139.00, $329.00
Sizes 20 µl, 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: PNPLA1 Antibody [NBP1-53193] - Titration: 0.2-1 ug/ml, Positive Control: COLO205 cell lysate.

PNPLA1 Antibody - H00285848-B01P from Novus Biologicals

Prices $359.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Western Blot: PNPLA1 Antibody [H00285848-B01P] - Analysis of PNPLA1 expression in human placenta.

PNPLA1 Polyclonal Antibody - bs-3742R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-PNPLA1 antibody produced in mouse - SAB1409144 from Sigma-Aldrich

Prices $347.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-PNPLA1: <B>Cat. No. SAB1409144</B>: Antibody concentration: 0.1-5 μg/mL. Specific band of ~49.1 kDa using PNPLA1 transfected 293T lysate.<BR/><B>Lanes</B><BR/>1. Transfected 293T lysate.<BR/>2. Non-transfected 293T lysate.

Anti-PNPLA1 antibody produced in rabbit - SAB2105719 from Sigma-Aldrich

Prices $347.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-PNPLA1: <B>Cat. No. SAB2105719</B>: PNPLA1 in COLO205 cell lysates with PNPLA1 antibody at 1.0 μg/mL.

Anti-PNPLA1 (401-414) antibody produced in rabbit - SAB1104726 from Sigma-Aldrich

Prices $285.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Lysate of HEK-293T cells overexpressing human PNPLA1 was separated on SDS-PAGE, blotted with Anti-PNPLA1 (401-414) (<B>Cat. No. SAB1104726</B>) and developed using Goat Anti-Rabbit IgG-Peroxidase (<B>Cat. No. A0545</B>) and a chemiluminescent substrate.<BR/><B>Lanes</B><BR/>1. Antibody dilution 1:1,000<BR/>2. Antibody dilution 1:1,000 + PNPLA1 immunizing peptide (human, 401-414)

Anti-PNPLA1 antibody produced in rabbit - HPA037853 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-PNPLA1: <B>Cat. No. HPA037853</B>: Immunohistochemical staining of human duodenum shows moderate cytoplasmic and membranous positivity in glandular cells.

PNPLA1 antibody - middle region (ARP49112_P050) - ARP49112_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

PNPLA1-Antibody-N-term - AP13348a from Abgent, a WuXi AppTec company

Prices $99.00, $295.00
Sizes 80 µl, 400 µl
Host Rabbit
Clonality Polyclonal
PNPLA1 Antibody (N-term) (Cat. #AP13348a) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the PNPLA1 antibody detected the PNPLA1 protein (arrow).

PNPLA1 Antibody - N-terminal region (OAAB09662) - OAAB09662 from Aviva Systems Biology

Prices $289.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal

PNPLA1 antibody - 70R-2936 from Fitzgerald

Prices $345.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
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