FOXP2

Gene Symbol FOXP2
Entrez Gene 93986
Alt Symbol CAGH44, SPCH1, TNRC10
Species Human
Gene Type protein-coding
Description forkhead box P2
Other Description CAG repeat protein 44|forkhead box protein P2|forkhead/winged-helix transcription factor|trinucleotide repeat containing 10|trinucleotide repeat-containing gene 10 protein
Swissprots Q8TD74 Q8NFQ2 Q75MJ3 B4DLD9 A0AUV6 Q8N0W2 Q8NFQ1 Q8NFQ4 Q8N6B7 Q8N6B8 Q8NFQ3 A4D0U8 Q6ZND1 O15409 Q8IZE0 A6NNW4
Accessions AAN03389 AAN03390 AAN03391 AAN03392 AAN03393 AAN03394 AAN03395 AAN03396 AAN03397 AAN03398 AAN03399 AAN03400 AAN03401 AAN03402 AAN03403 AAN03404 AAN03405 AAN03406 AAN03407 AAN03408 AAS07399 AAS07400 AAS07502 EAL24367 EAL24368 EAL24369 EAW83479 EAW83480 EAW83481 EAW83482 EAW83483 EAW83484 EAW83485 EAW83486 O15409 AF086040 AF337817 AAL10762 AF454830 AAM60761 AF467252 AAM60762 AF467253 AAM60763 AF467254 AAM60764 AF467255 AAM60765 AF467256 AAM60766 AF467257 AAM60767 AF467258 AAM60768 AF467259 AAM60769 AF493430 AAM13672 AI369947 AK131266 BAD18444 AK296957 BAG59501 AY144615 AAN60016 BC018016 BC126104 AAI26105 BC143866 AAI43867 BC143867 AAI43868 CR749236 CAH18092 DA400243 DQ778626 ABG77460 HQ258624 ADR83376 KJ534839 AHW56479 KJ535079 AHW56718 KJ535086 AHW56725 XM_011516706 XP_011515008 NM_001172766 NP_001166237 NM_001172767 NP_001166238 NM_014491 NP_055306 NM_148898 NP_683696 NM_148899 NP_683697 NM_148900 NP_683698 NR_033766 NR_033767
Function Transcriptional repressor that may play a role in the specification and differentiation of lung epithelium. May also play a role in developing neural, gastrointestinal and cardiovascular tissues. Can act with CTBP1 to synergistically repress transcription but CTPBP1 is not essential. Plays a role in synapse formation by regulating SRPX2 levels. Involved in neural mechanisms mediating the development of speech and language.
Subcellular Location Nucleus {ECO:0000305}.
Tissue Specificity Isoform 1 and isoform 6 are expressed in adult and fetal brain, caudate nucleus and lung. {ECO:0000269|PubMed:12189486}.

FoxP2 (D55H9) Rabbit mAb - 5337 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Monoclonal
Clone D55H9
Western blot analysis of extracts from 293 and HeLa cells using FoxP2 (D55H9) Rabbit mAb.

FOXP2 (C-17) - sc-31737 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

FOXP2 (H-90) - sc-66897 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
FOXP2 (H-90): sc-66897. Immunoperoxidase staining of formalin fixed, paraffin-embedded human cerebellum tissue showing nuclear and cytoplasmic staining of Purkinje cells and cytoplasmic staining of cells in molecular layer.

FOXP2 (N-16) - sc-21069 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-FOXP2 antibody - ab16046 from Abcam

Prices $401.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
IHC image of FOXP2 staining in mouse e17 foetal brain formalin fixed paraffin embedded tissue section, performed on a Leica Bond™ system using the standard protocol B. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH6, epitope retrieval solution 1) for 20 mins. The section was then incubated with ab16046, 0.1µg/ml, for 15 mins at room temperature. A goat anti-rabbit biotinylated secondary antibody was used to detect the primary, and visualized using an HRP conjugated ABC system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.For other IHC staining systems (automated and non-automated) customers should optimize variable parameters such as antigen retrieval conditions, primary antibody concentration and antibody incubation times.

Anti-FOXP2 antibody - ab1307 from Abcam

Prices $392.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
Anti-FOXP2 antibody (ab1307) at 0.5 µg/ml + Whole tissue lysate from human cerebellum (35µg protein in RIPA buffer)

Anti-FOXP2 antibody - ab58599 from Abcam

Prices $376.00
Sizes 200 µl
Host Goat
Clonality Polyclonal
Anti-FOXP2 antibody (ab58599) at 0.3 µg/ml + Human Brain (Cerebellum) lysate (35µg protein in RIPA buffer)

Anti-FOXP2 antibody - ab172320 from Abcam

Prices $376.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 73A/8
IHC image of FOXP2 staining in human lung formalin fixed paraffin embedded tissue section, performed on a Leica Bond system using the standard protocol F. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH6, epitope retrieval solution 1) for 20 mins. The section was then incubated with ab172320, 1µg/ml, for 15 mins at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.For other IHC staining systems (automated and non-automated) customers should optimize variable parameters such as antigen retrieval conditions, primary antibody concentration and antibody incubation times.

Anti-FOXP2 antibody [5C11A8] - ab119896 from Abcam

Host Mouse
Clonality Monoclonal
Clone 5C11A8
Anti-FOXP2 antibody [5C11A8] (ab119896) at 1/500 dilution + Human recombinant protein

Anti-FOXP2 antibody - C-terminal - ab175556 from Abcam

Prices $376.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-FOXP2 antibody - C-terminal (ab175556) at 1/1000 dilution + mouse heart tissue lysate at 15 µg

Anti-FOXP2 Antibody (aa484-497) IHC-plus™ - LS-B4346 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Goat
Clonality Polyclonal
Anti-FOXP2 antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B4346 concentration 2.5 ug/ml.

Anti-FOXP2 Antibody - LS-C6971 from LifeSpan Bioscience

Prices $285.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-FOXP2 Antibody - LS-C129175 from LifeSpan Bioscience

Prices $445.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-FOXP2 Antibody (clone 11C1034) - LS-C183856 from LifeSpan Bioscience

Prices $435.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone 11C1034
Human Testis: Formalin-Fixed, Paraffin-Embedded (FFPE)

Anti-FOXP2 Antibody (aa71-120) - LS-C31918 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
FOXP2 antibody LS-C31918 was used in IHC to stain formalin-fixed, paraffin-embedded human kidney.

Anti-FOXP2 Antibody (C-Terminus, AP) - LS-C214351 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-FOXP2 Antibody (C-Terminus, APC) - LS-C214353 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-FOXP2 Antibody (aa611-623) - LS-C54871 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
Antibody (0.5 ug/ml) staining of human cerebellum lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Anti-FOXP2 Antibody (C-Terminus, Biotin) - LS-C214354 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-FOXP2 Antibody (C-Terminus, FITC) - LS-C214355 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-FOXP2 Antibody (C-Terminus, PE) - LS-C214356 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-FOXP2 Antibody (aa657-684) - LS-C159677 from LifeSpan Bioscience

Prices $295.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
FOXP2 Antibody(Ascites)western blot of 293 cell line lysates (35 ug/lane). The FOXP2 antibody detected the FOXP2 protein (arrow).

Anti-FOXP2 Antibody (C-Terminus, Azide-free, HRP) - LS-C214357 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-FOXP2 Antibody (aa616-716) - LS-C307599 from LifeSpan Bioscience

Prices $455.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal

Anti-FOXP2 Antibody (C-Terminus) - LS-C321452 from LifeSpan Bioscience

Prices $435.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
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