PRMT2

Gene Symbol PRMT2
Entrez Gene 3275
Alt Symbol HRMT1L1
Species Human
Gene Type protein-coding
Description protein arginine methyltransferase 2
Other Description HMT1 (hnRNP methyltransferase, S. cerevisiae)-like 1|HMT1 hnRNP methyltransferase-like 1|PRMT2 alpha|PRMT2 beta|PRMT2 gamma|histone-arginine N-methyltransferase PRMT2|protein arginine N-methyltransferase 2
Swissprots Q6FHF0 B7U631 P78350 Q9BW15 P55345 Q99781 Q5U7D4 Q9UMC2 B7U632 Q498Y5 B7U630
Accessions CBX51391 EAX09258 EAX09259 EAX09260 EAX09261 EAX09262 EAX09263 EAX09264 EAX09265 P55345 AF059319 AAG43116 AI801643 AK055950 AK095641 AK123352 AK123650 BAG53931 AK124494 AK223157 BAD96877 AK312573 AL109794 CAB52454 AL833586 AY786414 AAV48568 BC000727 AAH00727 BC038765 AAH38765 BC100026 AAI00027 BF683143 BM976817 BQ267811 BQ421001 BY799824 CA427786 CB045875 CB529922 CN293838 CR541804 CAG46603 DA169949 DA517312 DA708321 DB160043 DQ892126 ABM83052 DQ895319 ABM86245 FJ436410 ACJ66866 FJ436411 ACJ66867 FJ436412 ACJ66868 U79286 AAB50221 U80213 AAB48437 X99209 CAA67599 XM_005261111 XP_005261168 XM_006723998 XP_006724061 XM_006723999 XP_006724062 XM_006724000 XP_006724063 NM_001242864 NP_001229793 NM_001242865 NP_001229794 NM_001242866 NP_001229795 NM_001286676 NP_001273605 NM_001286677 NP_001273606 NM_001286678 NP_001273607 NM_001535 NP_001526 NM_206962 NP_996845
Function Arginine methyltransferase that methylates the guanidino nitrogens of arginyl residues in proteins such as STAT3, FBL, histone H4. Acts as a coactivator (with NCOA2) of the androgen receptor (AR)-mediated transactivation. Acts as a coactivator (with estrogen) of estrogen receptor (ER)-mediated transactivation. Enhances PGR, PPARG, RARA-mediated transactivation. May inhibit NF-kappa-B transcription and promote apoptosis. Represses E2F1 transcriptional activity (in a RB1- dependent manner). May be involved in growth regulation. {ECO:0000269|PubMed:12039952, ECO:0000269|PubMed:16648481, ECO:0000269|PubMed:17587566, ECO:0000269|PubMed:19405910}.
Subcellular Location Isoform PRMT2L2: Cytoplasm {ECO:0000269|PubMed:21820040}. Nucleus {ECO:0000269|PubMed:21820040}. Note=Predominantly cytoplasmic.
Tissue Specificity Widely expressed. Highly expressed in androgen target organs such as heart, prostate, skeletal muscle, ovary and spinal cord. {ECO:0000269|PubMed:17587566}.

PRMT2 CRISPR/Cas9 KO Plasmid (h) - sc-405107 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

PRMT2 HDR Plasmid (h) - sc-405107-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PRMT2 Double Nickase Plasmid (h) - sc-405107-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PRMT2 Double Nickase Plasmid (h2) - sc-405107-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PRMT2 CRISPR Activation Plasmid (h) - sc-405107-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

PRMT2 CRISPR Activation Plasmid (h2) - sc-405107-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

PRMT2 Lentiviral Activation Particles (h) - sc-405107-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PRMT2 Lentiviral Activation Particles (h2) - sc-405107-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PRMT2 siRNA (h) - sc-62860 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

PRMT2 shRNA Plasmid (h) - sc-62860-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

PRMT2 shRNA (h) Lentiviral Particles - sc-62860-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU134801 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN17442 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND17442 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

PRMT2 siRNA (Human) - CRH2241 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human PRMT2 (NM_001535.3) - SHH383332 from Creative biogene

Category siRNA
Species Reactivities Human

Human PRMT2 siRNA - orb262743 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

PRMT2 shRNA Plasmid (Human) - CHH2241 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

PRMT2 miRNA 3'UTR clone - MiUTR3H-04533 from Creative biogene

Species Reactivities Human

PRMT2 miRNA 3'UTR clone - MiUTR3H-04534 from Creative biogene

Species Reactivities Human
Search more