| Gene Symbol |
PPP1R14D
|
| Entrez Gene |
54866
|
| Alt Symbol |
CPI17-like, GBPI-1, GBPI1
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
protein phosphatase 1, regulatory (inhibitor) subunit 14D
|
| Other Description |
PKC-dependent PP1 inhibitory protein|gastrointestinal and brain-specific PP1-inhibitory protein 1|gut and brain phosphatase inhibitor 1|protein phosphatase 1 regulatory subunit 14D
|
| Swissprots |
Q9NXH3 Q4V773
|
| Accessions |
EAW92456 Q9NXH3 AI963626 AK000258 BAA91037 AY050671 AAL25829 BC096716 AAH96716 BC098124 AAH98124 BC098150 AAH98150 BC098341 AAH98341 NM_001130143 NP_001123615 NM_017726 NP_060196
|
| Function |
Inhibitor of PPP1CA. Has inhibitory activity only when phosphorylated, creating a molecular switch for regulating the phosphorylation status of PPP1CA substrates and smooth muscle contraction. {ECO:0000269|PubMed:12974676}.
|
| Subcellular Location |
Cytoplasm {ECO:0000305}.
|
| Tissue Specificity |
Detected in colon, intestine, kidney and brain cortex. {ECO:0000269|PubMed:12974676}.
|
![Western Blot: PPP1R14D/GBPI-1 Overexpression Lysate (Adult Normal) [NBP2-06935] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for PPP1R14D/GBPI-1.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/1660_PPP1R14D-GBPI-1%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBP2-06935-img0001.jpg)