Gene Symbol | PPP1R14D |
---|---|
Entrez Gene | 54866 |
Alt Symbol | CPI17-like, GBPI-1, GBPI1 |
Species | Human |
Gene Type | protein-coding |
Description | protein phosphatase 1, regulatory (inhibitor) subunit 14D |
Other Description | PKC-dependent PP1 inhibitory protein|gastrointestinal and brain-specific PP1-inhibitory protein 1|gut and brain phosphatase inhibitor 1|protein phosphatase 1 regulatory subunit 14D |
Swissprots | Q9NXH3 Q4V773 |
Accessions | EAW92456 Q9NXH3 AI963626 AK000258 BAA91037 AY050671 AAL25829 BC096716 AAH96716 BC098124 AAH98124 BC098150 AAH98150 BC098341 AAH98341 NM_001130143 NP_001123615 NM_017726 NP_060196 |
Function | Inhibitor of PPP1CA. Has inhibitory activity only when phosphorylated, creating a molecular switch for regulating the phosphorylation status of PPP1CA substrates and smooth muscle contraction. {ECO:0000269|PubMed:12974676}. |
Subcellular Location | Cytoplasm {ECO:0000305}. |
Tissue Specificity | Detected in colon, intestine, kidney and brain cortex. {ECO:0000269|PubMed:12974676}. |