Gene Symbol | PPP1R14D |
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Entrez Gene | 54866 |
Alt Symbol | CPI17-like, GBPI-1, GBPI1 |
Species | Human |
Gene Type | protein-coding |
Description | protein phosphatase 1, regulatory (inhibitor) subunit 14D |
Other Description | PKC-dependent PP1 inhibitory protein|gastrointestinal and brain-specific PP1-inhibitory protein 1|gut and brain phosphatase inhibitor 1|protein phosphatase 1 regulatory subunit 14D |
Swissprots | Q9NXH3 Q4V773 |
Accessions | EAW92456 Q9NXH3 AI963626 AK000258 BAA91037 AY050671 AAL25829 BC096716 AAH96716 BC098124 AAH98124 BC098150 AAH98150 BC098341 AAH98341 NM_001130143 NP_001123615 NM_017726 NP_060196 |
Function | Inhibitor of PPP1CA. Has inhibitory activity only when phosphorylated, creating a molecular switch for regulating the phosphorylation status of PPP1CA substrates and smooth muscle contraction. {ECO:0000269|PubMed:12974676}. |
Subcellular Location | Cytoplasm {ECO:0000305}. |
Tissue Specificity | Detected in colon, intestine, kidney and brain cortex. {ECO:0000269|PubMed:12974676}. |
PPP1R14D CRISPR/Cas9 KO Plasmid (h) - sc-412358 from Santa Cruz Biotechnology
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PPP1R14D HDR Plasmid (h) - sc-412358-HDR from Santa Cruz Biotechnology
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PPP1R14D Double Nickase Plasmid (h) - sc-412358-NIC from Santa Cruz Biotechnology
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PPP1R14D Double Nickase Plasmid (h2) - sc-412358-NIC-2 from Santa Cruz Biotechnology
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PPP1R14D CRISPR Activation Plasmid (h) - sc-412358-ACT from Santa Cruz Biotechnology
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PPP1R14D CRISPR Activation Plasmid (h2) - sc-412358-ACT-2 from Santa Cruz Biotechnology
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PPP1R14D Lentiviral Activation Particles (h) - sc-412358-LAC from Santa Cruz Biotechnology
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PPP1R14D Lentiviral Activation Particles (h2) - sc-412358-LAC-2 from Santa Cruz Biotechnology
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PPP1R14D siRNA (h) - sc-90122 from Santa Cruz Biotechnology
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PPP1R14D shRNA Plasmid (h) - sc-90122-SH from Santa Cruz Biotechnology
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PPP1R14D shRNA (h) Lentiviral Particles - sc-90122-V from Santa Cruz Biotechnology
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MISSION® Human Phosphatase - SIHP0550 from Sigma-Aldrich
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MISSION® Human Phosphatase - SIHP0552 from Sigma-Aldrich
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MISSION® Human Phosphatase - SIHP0551 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN17267 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND17267 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR01122 from Sigma-Aldrich
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PPP1R14D siRNA (Human) - CRJ0278 from Cohesion Biosciences
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shRNA set against Human PPP1R14D (NM_017726.7) - SHH381100 from Creative biogene
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PPP1R14D shRNA Plasmid (Human) - CHJ0278 from Cohesion Biosciences
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PPP1R14D miRNA 3'UTR clone - MiUTR4H-TG06957 from Creative biogene
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