Gene Symbol | CEP55 |
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Entrez Gene | 55165 |
Alt Symbol | C10orf3, CT111, URCC6 |
Species | Human |
Gene Type | protein-coding |
Description | centrosomal protein 55kDa |
Other Description | cancer/testis antigen 111|centrosomal protein of 55 kDa|up-regulated in colon cancer 6 |
Swissprots | B2RDG8 Q3MV20 Q53EZ4 Q96H32 Q9NVS7 Q6N034 Q32WF5 Q5VY28 |
Accessions | CAJ29952 CAN87445 CAN87446 CAN87449 CAN87453 EAW50071 EAW50072 Q53EZ4 AB091343 BAE45243 AK001402 BAA91670 AK223495 BAD97215 AK315536 BAG37915 AY788918 AAX14687 BC008947 AAH08947 BX640718 CAE45837 DA545074 HQ447335 ADQ31821 XM_011539918 XP_011538220 XM_011539919 XP_011538221 XM_011539920 XP_011538222 NM_001127182 NP_001120654 NM_018131 NP_060601 |
Function | Plays a role in mitotic exit and cytokinesis. Not required for microtubule nucleation. Recruits PDCD6IP and TSG101 to midbody during cytokinesis. {ECO:0000269|PubMed:16198290, ECO:0000269|PubMed:17853893}. |
Subcellular Location | Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cleavage furrow. Midbody. Note=Present at the centrosomes at interphase. A small portion is associated preferentially with the mother centriole, whereas the majority localizes to the pericentriolar material. During mitosis, loss of affinity for the centrosome at the onset of prophase and diffusion throughout the cell. This dissociation from the centrosome is phosphorylation-dependent. May remain localized at the centrosome during mitosis in certain cell types. Appears at the cleavage furrow in late anaphase and in the midbody in cytokinesis. |
Tissue Specificity | Widely expressed, mostly in proliferative tissues. Highly expressed in testis. Intermediate levels in adult and fetal thymus, as well as in various cancer cell lines. Low levels in different parts of the digestive tract, bone marrow, lymph nodes, placenta, fetal heart and fetal spleen. Hardly detected in brain. {ECO:0000269|PubMed:16198290, ECO:0000269|PubMed:16406728}. |
Human CEP55 full length protein - ab162993 from Abcam
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CEP55 Antibody Blocking Peptide - LS-E16877 from LifeSpan Bioscience
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CEP55 Antibody Blocking Peptide - LS-E16878 from LifeSpan Bioscience
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CEP55 Antibody Blocking Peptide - LS-E9658 from LifeSpan Bioscience
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Recombinant Human CEP55 Protein - H00055165-P01 from Novus Biologicals
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CEP55-Antibody-N-term-Blocking-Peptide - BP8586a from Abgent, a WuXi AppTec company
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CEP55 Blocking Peptide - 33R-9162 from Fitzgerald
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CEP55 Blocking Peptide - 33R-6509 from Fitzgerald
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CEP55 - H00055165-P01-10 from Acris Antibodies
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CEP55 - H00055165-P01-25 from Acris Antibodies
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CEP55 fusion protein - Ag20940 from Proteintech Group
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CEP55 fusion protein - ag13465 from Proteintech Group
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Recombinant Human Centrosomal protein of 55 kDa(CEP55) - CSB-YP709600HU CSB-EP709600HU CSB-BP709600HU CSB-MP709600HU from Cusabio
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CEP55 Protein - abx163150 from Abbexa
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CEP55 (transcript variant 1) - TP301052 from Acris Antibodies
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Centrosomal protein of 55 kDa (CEP55), Recombinant Protein - MBS1479219 from MyBioSource
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CEP55 Recombinant Protein Antigen - NBP1-91778PEP from Novus Biologicals
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CEP55 Peptide, Human - M34GP02996H from Creative Peptides
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Centrosomal Protein 55kDa (CEP55), Recombinant Protein - MBS2086903 from MyBioSource
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