Gene Symbol | CEP55 |
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Entrez Gene | 55165 |
Alt Symbol | C10orf3, CT111, URCC6 |
Species | Human |
Gene Type | protein-coding |
Description | centrosomal protein 55kDa |
Other Description | cancer/testis antigen 111|centrosomal protein of 55 kDa|up-regulated in colon cancer 6 |
Swissprots | B2RDG8 Q3MV20 Q53EZ4 Q96H32 Q9NVS7 Q6N034 Q32WF5 Q5VY28 |
Accessions | CAJ29952 CAN87445 CAN87446 CAN87449 CAN87453 EAW50071 EAW50072 Q53EZ4 AB091343 BAE45243 AK001402 BAA91670 AK223495 BAD97215 AK315536 BAG37915 AY788918 AAX14687 BC008947 AAH08947 BX640718 CAE45837 DA545074 HQ447335 ADQ31821 XM_011539918 XP_011538220 XM_011539919 XP_011538221 XM_011539920 XP_011538222 NM_001127182 NP_001120654 NM_018131 NP_060601 |
Function | Plays a role in mitotic exit and cytokinesis. Not required for microtubule nucleation. Recruits PDCD6IP and TSG101 to midbody during cytokinesis. {ECO:0000269|PubMed:16198290, ECO:0000269|PubMed:17853893}. |
Subcellular Location | Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cleavage furrow. Midbody. Note=Present at the centrosomes at interphase. A small portion is associated preferentially with the mother centriole, whereas the majority localizes to the pericentriolar material. During mitosis, loss of affinity for the centrosome at the onset of prophase and diffusion throughout the cell. This dissociation from the centrosome is phosphorylation-dependent. May remain localized at the centrosome during mitosis in certain cell types. Appears at the cleavage furrow in late anaphase and in the midbody in cytokinesis. |
Tissue Specificity | Widely expressed, mostly in proliferative tissues. Highly expressed in testis. Intermediate levels in adult and fetal thymus, as well as in various cancer cell lines. Low levels in different parts of the digestive tract, bone marrow, lymph nodes, placenta, fetal heart and fetal spleen. Hardly detected in brain. {ECO:0000269|PubMed:16198290, ECO:0000269|PubMed:16406728}. |
CEP55 (B-8) - sc-374051 from Santa Cruz Biotechnology
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CEP55 (E-14) - sc-162675 from Santa Cruz Biotechnology
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CEP55 (H-300) - sc-134622 from Santa Cruz Biotechnology
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CEP55 (M-300) - sc-134623 from Santa Cruz Biotechnology
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Anti-CEP55 antibody - ab84580 from Abcam
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Anti-CEP55 antibody - ab91469 from Abcam
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Anti-CEP55 antibody - ab169679 from Abcam
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Anti-CEP55 antibody - ab136028 from Abcam
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Anti-CEP55 antibody - ab154632 from Abcam
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Anti-CEP55 antibody [EPR11944(B)] - ab170414 from Abcam
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Anti-CEP55 Antibody (N-Terminus, APC) - LS-C243919 from LifeSpan Bioscience
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Anti-CEP55 Antibody (N-Terminus, AP) - LS-C243918 from LifeSpan Bioscience
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Anti-CEP55 Antibody (N-Terminus, Biotin) - LS-C243920 from LifeSpan Bioscience
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Anti-CEP55 Antibody (N-Terminus, PE) - LS-C243925 from LifeSpan Bioscience
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Anti-CEP55 Antibody (N-Terminus, FITC) - LS-C243921 from LifeSpan Bioscience
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Anti-CEP55 Antibody (N-Terminus, Azide-free, HRP) - LS-C247486 from LifeSpan Bioscience
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Anti-CEP55 Antibody (aa69-118) - LS-C291793 from LifeSpan Bioscience
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Anti-CEP55 Antibody - LS-C307786 from LifeSpan Bioscience
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Anti-CEP55 Antibody - LS-C309881 from LifeSpan Bioscience
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Anti-CEP55 Antibody (N-Terminus) - LS-C80872 from LifeSpan Bioscience
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Anti-CEP55 Antibody - LS-C309883 from LifeSpan Bioscience
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Anti-CEP55 Antibody (N-Terminus) - LS-C327053 from LifeSpan Bioscience
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Anti-CEP55 Antibody - LS-C168678 from LifeSpan Bioscience
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Anti-CEP55 Antibody (aa360-409) - LS-C102216 from LifeSpan Bioscience
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Anti-CEP55 Antibody (aa81-130) - LS-C119833 from LifeSpan Bioscience
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