| Gene Symbol |
ARHGAP5
|
| Entrez Gene |
394
|
| Alt Symbol |
GFI2, RhoGAP5, p190-B, p190BRhoGAP
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
Rho GTPase activating protein 5
|
| Other Description |
growth factor independent 2|p100 RasGAP-associated p105 protein|p105 RhoGAP|rho GTPase-activating protein 5|rho-type GTPase-activating protein 5
|
| Swissprots |
D3DS89 Q05BU8 D3DS90 A1L376 Q59ER0 Q6DHZ3 A1L375 Q13017 A8KAA1 Q05BE8
|
| Accessions |
CCQ43130 EAW65935 EAW65936 EAW65937 EAW65938 Q13017 AB209751 BAD92988 AK023014 AK023468 AK292966 BAF85655 AK307454 AL045112 AY316523 AAP83192 BC032723 AAH32723 BC050059 AAH50059 BC075799 AAH75799 BC129928 AAI29929 BC129929 AAI29930 CA945100 U17032 AAA95963 XM_005267635 XP_005267692 XM_005267636 XP_005267693 NM_001030055 NP_001025226 NM_001173 NP_001164
|
| Function |
GTPase-activating protein for Rho family members. May play a role in the reduction of the p21rasGTPase-activating potential of RASA1/p120GAP.
|
| Subcellular Location |
Cytoplasm. Membrane; Peripheral membrane protein. Note=Also membrane-associated when found in fibrillar patterns that colocalize with the alpha5-beta1 integrin receptor (ITGA5/ITGB1) for fibronectin.
|
| Tissue Specificity |
Expressed in kidney, brain, liver and lung.
|
| Top Pathways |
Focal adhesion, Leukocyte transendothelial migration
|